Nuclear magnetic resonance spectroscopy reveals dysregulation of monounsaturated fatty acid metabolism upon SPINK1 attenuation in colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4705
Abstract: Metabolic reprogramming, a key hallmark of cancer, plays a pivotal role in fulfilling the accelerated biological demands of tumor cells. Such metabolic changes trigger the production of several proinflammatory factors, thereby inciting cancer development and… read more here.
Keywords: spectroscopy; crc; colorectal cancer; monounsaturated fatty ... See more keywords
Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular cell"
DOI: 10.1016/j.molcel.2019.12.003
Abstract: Lipid droplets (LDs) provide a reservoir for triacylglycerol storage and are a central hub for fatty acid trafficking and signaling in cells. Lipolysis promotes mitochondrial biogenesis and oxidative metabolism via a SIRT1/PGC-1α/PPARα-dependent pathway through an… read more here.
Keywords: allosterically activate; activate sirt1; fatty acids; derived monounsaturated ... See more keywords
Divergent evolution of extreme production of variant plant monounsaturated fatty acids
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2201160119
Abstract: Significance The dietary and oleochemical value of vegetable oils is determined by their component fatty acids. Double bonds or “unsaturation” in fatty acids are critical for vegetable oil functionality. Seeds containing vegetable oils with extremely… read more here.
Keywords: extreme production; divergent evolution; evolution extreme; fatty acids ... See more keywords
Increasing Monounsaturated Fatty Acid Contents in Hexaploid Camelina sativa Seed Oil by FAD2 Gene Knockout Using CRISPR-Cas9
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.702930
Abstract: Seed oils are used as edible oils and increasingly also for industrial applications. Although high-oleic seed oil is preferred for industrial use, most seed oil is high in polyunsaturated fatty acids (PUFAs) and low in… read more here.
Keywords: seed; camelina; cas9; monounsaturated fatty ... See more keywords
Higher Availability of Long-Chain Monounsaturated Fatty Acids in Preterm than in Full-Term Human Milk
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13051205
Abstract: While the role of n-3 and n-6 long-chain polyunsaturated fatty acids (LCPUFAs) in the maturation of the infantile nervous system is extensively studied and relatively well-characterized, data on the potential developmental importance of the n-9… read more here.
Keywords: long chain; fatty acids; chain monounsaturated; monounsaturated fatty ... See more keywords
Glycated Proteins, Glycine, Acetate, and Monounsaturated Fatty Acids May Act as New Biomarkers to Predict the Progression of Type 2 Diabetes: Secondary Analyses of a Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14235165
Abstract: Food protein or food-derived peptides may regulate blood glucose levels; however, studies have shown inconsistent results. The aim of the present study was to characterize subgroups of individuals with increased risk of type 2 diabetes… read more here.
Keywords: fish protein; randomized controlled; type diabetes; monounsaturated fatty ... See more keywords
Comparison of the Effects of Long-chain Monounsaturated Fatty Acid Positional Isomers on Lipid Metabolism in 3T3-L1 Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of oleo science"
DOI: 10.5650/jos.ess18223
Abstract: Long chain monounsaturated fatty acids (LC-MUFAs) have shown beneficial health effects in previous studies. They occur as mixtures of positional isomers (PIs) in food. The functionalities of LC-MUFA PIs have not been studied extensively. Common… read more here.
Keywords: chain; long chain; chain monounsaturated; lipid metabolism ... See more keywords
Reducing lipid bilayer stress by monounsaturated fatty acids protects renal proximal tubules in diabetes
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.74391
Abstract: In diabetic patients, dyslipidemia frequently contributes to organ damage such as diabetic kidney disease (DKD). Dyslipidemia is associated with both excessive deposition of triacylglycerol (TAG) in lipid droplets (LDs) and lipotoxicity. Yet, it is unclear… read more here.
Keywords: renal proximal; stress; bilayer stress; fatty acids ... See more keywords