Population Pharmacokinetic Modeling and Probability of Pharmacodynamic Target Attainment for Ceftazidime-Avibactam in Pediatric Patients Aged 3 Months and Older.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2460
Abstract: Increasing prevalence of infections caused by antimicrobial-resistant Gram-negative bacteria represents a global health crisis, and while several novel therapies that target various aspects of antimicrobial resistance have been introduced in recent years, few are currently… read more here.
Keywords: ceftazidime avibactam; months older; population pharmacokinetic; avibactam pediatric ... See more keywords
Stiripentol for the treatment of seizures associated with Dravet syndrome in patients 6 months and older and taking clobazam
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2023.2195550
Abstract: ABSTRACT Introduction Stiripentol (STP) is a structurally unique molecule with anticonvulsant and neuroprotective properties in animal and human studies. STP enhances gamma-aminobutyric acid (GABA)ergic neurotransmission and inhibits multiple hepatic isoenzymes (i.e. cytochrome P450 system) involved… read more here.
Keywords: stiripentol treatment; treatment seizures; stp; dravet syndrome ... See more keywords