The Use of Proteomics Studies in Identifying Moonlighting Proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8814-3_25
Abstract: Proteomics studies that characterize hundreds or thousands of proteins in parallel can play an important part in the identification of moonlighting proteins, proteins that perform two or more distinct and physiologically relevant biochemical or biophysical… read more here.
Keywords: proteomics studies; use proteomics; studies identifying; identifying moonlighting ... See more keywords
MoonProt 3.0: an update of the moonlighting proteins database
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DOI: 10.1093/nar/gkaa1101
Abstract: Abstract MoonProt 3.0 (http://moonlightingproteins.org) is an updated open-access database storing expert-curated annotations for moonlighting proteins. Moonlighting proteins have two or more physiologically relevant distinct biochemical or biophysical functions performed by a single polypeptide chain. Here,… read more here.
Keywords: proteins database; moonprot update; update moonlighting; moonlighting proteins ... See more keywords
Protein moonlighting: what is it, and why is it important?
Sign Up to like & getrecommendations! Published in 2017 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2016.0523
Abstract: Members of the GroEL/HSP60 protein family have been studied for many years because of their critical roles as ATP-dependent molecular chaperones, so it might come as a surprise that some have important functions in ATP-poor… read more here.
Keywords: protein; protein moonlighting; moonlighting important; function ... See more keywords
Sharing of Moonlighting Proteins Mediates the Symbiotic Relationship among Intestinal Commensals
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DOI: 10.1128/aem.02190-22
Abstract: The adhesion of intestinal bacteria to the mucus layer is an important colonization strategy in the gut environment. Generally, the bacterial adhesion process is a characteristic feature of the individual cell surface-associated adhesion factors secreted… read more here.
Keywords: symbiotic relationship; adhesion; cell surface; thetaiotaomicron ... See more keywords
De novo Prediction of Moonlighting Proteins Using Multimodal Deep Ensemble Learning
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DOI: 10.3389/fgene.2021.630379
Abstract: Moonlighting proteins (MPs) are a special type of protein with multiple independent functions. MPs play vital roles in cellular regulation, diseases, and biological pathways. At present, very few MPs have been discovered by biological experiments.… read more here.
Keywords: novo prediction; multimodal deep; deep ensemble; ensemble learning ... See more keywords
A method for identifying moonlighting proteins based on linear discriminant analysis and bagging-SVM
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.963349
Abstract: Moonlighting proteins have at least two independent functions and are widely found in animals, plants and microorganisms. Moonlighting proteins play important roles in signal transduction, cell growth and movement, tumor inhibition, DNA synthesis and repair,… read more here.
Keywords: discriminant analysis; linear discriminant; method identifying; identifying moonlighting ... See more keywords
Moonlighting proteins in medically relevant fungi
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DOI: 10.7717/peerj.14001
Abstract: Moonlighting proteins represent an intriguing area of cell biology, due to their ability to perform two or more unrelated functions in one or many cellular compartments. These proteins have been described in all kingdoms of… read more here.
Keywords: medically relevant; proteins medically; relevant fungi; biology ... See more keywords