The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells
Sign Up to like & getrecommendations! Published in 2018 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-017-2065-9
Abstract: BackgroundBehavioral studies demonstrated that the administration of Withania somnifera Dunal roots extract (WSE), prolongs morphine-elicited analgesia and reduces the development of tolerance to the morphine’s analgesic effect; however, little is known about the underpinning molecular… read more here.
Keywords: morphine; withania somnifera; mop nop; gene expression ... See more keywords
MOP and NOP receptor interaction: Studies with a dual expression system and bivalent peptide ligands
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0260880
Abstract: Opioids targeting mu;μ (MOP) receptors produce analgesia in the peri-operative period and palliative care. They also produce side effects including respiratory depression, tolerance/dependence and addiction. The N/OFQ opioid receptor (NOP) also produces analgesia but is… read more here.
Keywords: interaction; expression system; hekmop nop; mop nop ... See more keywords