Non-Peptide Opioids Differ in Effects on Mu-Opioid (MOP) and Serotonin 1A (5-HT1A) Receptors Heterodimerization and Cellular Effectors (Ca2+, ERK1/2 and p38) Activation
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DOI: 10.3390/molecules27072350
Abstract: The importance of the dynamic interplay between the opioid and the serotonin neuromodulatory systems in chronic pain is well recognized. In this study, we investigated whether these two signalling pathways can be integrated at the… read more here.
Keywords: peptide opioids; ht1a receptors; opioid mop; mop serotonin ... See more keywords