Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39374-0
Abstract: Moraxella catarrhalis is a host-adapted bacterial pathogen that causes otitis media and exacerbations of chronic obstructive pulmonary disease. This study characterises the conserved M. catarrhalis extracellular nuclease, a member of the ββα metal finger family… read more here.
Keywords: catarrhalis nucm; catarrhalis; moraxella catarrhalis; entry nuclease ... See more keywords
An integrated complete-genome sequencing and systems biology approach to predict antimicrobial resistance genes in the virulent bacterial strains of Moraxella catarrhalis.
Sign Up to like & getrecommendations! Published in 2023 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elad005
Abstract: Moraxella catarrhalis is a symbiotic as well as mucosal infection-causing bacterium unique to humans. Currently, it is considered as one of the leading factors of acute middle ear infection in children. As M. catarrhalis is… read more here.
Keywords: bacterial strains; catarrhalis; moraxella catarrhalis; antimicrobial resistance ... See more keywords
The characterization of Moraxella catarrhalis carried in the general population
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000820
Abstract: Moraxella catarrhalis is a common cause of respiratory tract infection, particularly otitis media in children, whilst it is also associated with the onset of exacerbation in chronic obstructive pulmonary disease in adults. Despite the need… read more here.
Keywords: prevalence; catarrhalis; catarrhalis carried; moraxella catarrhalis ... See more keywords
Virulence determinants of Moraxella catarrhalis: distribution and considerations for vaccine development.
Sign Up to like & getrecommendations! Published in 2017 at "Microbiology"
DOI: 10.1099/mic.0.000523
Abstract: Moraxella catarrhalis is a human-restricted opportunistic bacterial pathogen of the respiratory mucosa. It frequently colonizes the nasopharynx asymptomatically, but is also an important causative agent of otitis media (OM) in children, and plays a significant… read more here.
Keywords: virulence; virulence factors; catarrhalis; moraxella catarrhalis ... See more keywords
Molecular Characterization of Fluoroquinolone-Resistant Moraxella catarrhalis Variants Generated In Vitro by Stepwise Selection
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01336-17
Abstract: ABSTRACT Moraxella catarrhalis causes respiratory infections. In this study, fluoroquinolone-resistant strains were selected in vitro to evaluate the mechanism of fluoroquinolone resistance. Strains with reduced fluoroquinolone susceptibility were obtained by stepwise selection in levofloxacin, and… read more here.
Keywords: fluoroquinolone; moraxella catarrhalis; fluoroquinolone resistant; stepwise selection ... See more keywords
Rothia from the Human Nose Inhibit Moraxella catarrhalis Colonization with a Secreted Peptidoglycan Endopeptidase
Sign Up to like & getrecommendations! Published in 2023 at "mBio"
DOI: 10.1128/mbio.00464-23
Abstract: Moraxella catarrhalis is a pathobiont of the respiratory tract, responsible for ear infections in children and wheezing illnesses in children and adults with chronic respiratory diseases. Detection of M. catarrhalis during wheezing episodes in early… read more here.
Keywords: rothia; catarrhalis; moraxella catarrhalis; respiratory ... See more keywords
Hockey puck sign: identifying Moraxella catarrhalis
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-243677
Abstract: © BMJ Publishing Group Limited 2021. No commercial reuse. See rights and permissions. Published by BMJ. DESCRIPTION A 76yearold male patient with diabetes mellitus presented with a 4day history of productive cough and fever. He… read more here.
Keywords: catarrhalis; puck sign; moraxella catarrhalis; hockey puck ... See more keywords
Mucin Binding to Moraxella catarrhalis During Airway Inflammation is Dependent on Sialic Acid.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2021-0064oc
Abstract: Chronic obstructive pulmonary disease (COPD) is associated with colonization by bacterial pathogens and repeated airway infections, leading to exacerbations and impaired lung function. The highly glycosylated mucins in the mucus lining the airways are an… read more here.
Keywords: airway; moraxella catarrhalis; copd; inflammation ... See more keywords
Subtractive genomics profiling for potential drug targets identification against Moraxella catarrhalis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0273252
Abstract: Moraxella catarrhalis (M. catarrhalis) is a gram-negative bacterium, responsible for major respiratory tract and middle ear infection in infants and adults. The recent emergence of the antibiotic resistance M. catarrhalis demands the prioritization of an… read more here.
Keywords: moraxella catarrhalis; subtractive genomics; drug; drug targets ... See more keywords
Mutation of TonB-Dependent Receptor Encoding Gene MCR_0492 Potentially Associates with Macrolides Resistance in Moraxella catarrhalis Isolates
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s364397
Abstract: Introduction Moraxella catarrhalis, which is an opportunistic pathogen and is one of the three major pathogens of community-acquired pneumonia, causes a variety of infections in clinic. In recent years, the isolation rate of Moraxella catarrhalis… read more here.
Keywords: moraxella; moraxella catarrhalis; resistance; tonb dependent ... See more keywords
Rhinovirus increases Moraxella catarrhalis adhesion to the respiratory epithelium
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1060748
Abstract: Rhinovirus causes many types of respiratory illnesses, ranging from minor colds to exacerbations of asthma. Moraxella catarrhalis is an opportunistic pathogen that is increased in abundance during rhinovirus illnesses and asthma exacerbations and is associated… read more here.
Keywords: infection; rhinovirus; moraxella catarrhalis; respiratory epithelium ... See more keywords