Neural Glyoxalase Pathway Enhancement by Morin Derivatives in an Alzheimer's Disease Model.
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DOI: 10.1021/acschemneuro.9b00566
Abstract: The gyloxalase pathway (GP) is an antioxidant defense system that detoxifies metabolic byproduct methylglyoxal (MG). Through sequential reactions, reduced glutathione (GSH), glyoxalase I (glo-1), and glyoxalase II (glo-2) convert MG into D-lactate. Spontaneous reactions involving… read more here.
Keywords: glyoxalase; alzheimer disease; pathway; morin derivatives ... See more keywords