Codeine 3-O-demethylase catalyzed biotransformation of morphinan alkaloids in Escherichia coli: site directed mutagenesis of terminal residues improves enzyme expression, stability and biotransformation yield
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DOI: 10.1186/s13036-025-00477-0
Abstract: The cultivation of opium poppy is the only commercially viable source of most morphinan alkaloids. Bioproduction of morphinan alkaloids in recombinant whole-cell systems provides a promising alternate source of these valuable compounds. The enzyme codeine… read more here.
Keywords: codeine demethylase; biotransformation; demethylase; morphinan alkaloids ... See more keywords