The role of hippocampal glial glutamate transporter (GLT‐1) in morphine‐induced behavioral responses
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DOI: 10.1002/brb3.2323
Abstract: Opioid abuse modifies synaptic plasticity, which leads to behavioral changes, such as morphine dependence, but the mechanism remains poorly understood. Glial cells play an important role in the modulation of synaptic plasticity and are involved… read more here.
Keywords: glt; morphine dependence; glutamate; role hippocampal ... See more keywords
Central antagonism of orexin type-1 receptors attenuates the development of morphine dependence in rat locus coeruleus neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.08.054
Abstract: Prolonged use/abuse of opioid agonists leads to development of severe dependence to these drugs. Orexin-A has a crucial role in development of morphine dependence. The locus coeruleus (LC) is implicated in the expression of morphine… read more here.
Keywords: morphine dependence; dependence; morphine; locus coeruleus ... See more keywords
Effectiveness and safety of repetitive transcranial magnetic stimulation for the treatment of morphine dependence
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DOI: 10.1097/md.0000000000025208
Abstract: Abstract Morphine dependence (MD) is a very common complication because of the chronic morphine consumption. Studies suggest that repetitive transcranial magnetic stimulation (rTMS) can be used for the treatment of MD. However, there is still… read more here.
Keywords: morphine dependence; repetitive transcranial; treatment; effectiveness ... See more keywords
MicroRNA-132 is involved in morphine dependence via modifying the structural plasticity of the dentate gyrus neurons in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Addiction biology"
DOI: 10.1111/adb.13086
Abstract: Repeated morphine exposure has been shown to induce neuronal plasticity in reward-related areas of the brain. miR-132, a CREB-induced and activation-dependent microRNA, has been suggested to be involved in the neuronal plasticity by increasing neuronal… read more here.
Keywords: morphine dependence; plasticity; mir 132; involved morphine ... See more keywords
MiR-124 Regulates IQGAP1 and Participates in the Relationship Between Morphine Dependence Susceptibility and Cognition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.845357
Abstract: Background Long-term excessive use of morphine leads to addictive diseases and affects cognitive function. Cognitive performance is associated with genetic characteristics.MiR-124 plays a critical regulatory role in neurogenesis, synaptic development, brain plasticity, and the use… read more here.
Keywords: morphine dependence; cognitive function; mir 124; cognition ... See more keywords