Robust tissue pattern formation by coupling morphogen signal and cell adhesion
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DOI: 10.1038/s44319-024-00261-z
Abstract: Morphogens, locally produced signaling molecules, form a concentration gradient to guide tissue patterning. Tissue patterns emerge as a collaboration between morphogen diffusion and responsive cell behaviors, but the mechanisms through which diffusing morphogens define precise… read more here.
Keywords: morphogen gradient; adhesion; morphogen; cell ... See more keywords
Multiple dynamic modes of Bicoid morphogen gradient are explained by a quantum-classical model
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DOI: 10.1063/5.0221207
Abstract: Extracellular diffusion coupled with degradation is considered a dominant mechanism behind the establishment of morphogen gradients. However, the fundamental nature of these biophysical processes, visa viz, the Bicoid (Bcd) morphogen gradient, remains unclear. Fluorescence correlation… read more here.
Keywords: morphogen gradient; morphogen; dynamic modes; gradient ... See more keywords
Bidirectional transport model of morphogen gradient formation via cytonemes.
Sign Up to like & getrecommendations! Published in 2018 at "Physical biology"
DOI: 10.1088/1478-3975/aaa64c
Abstract: Morphogen protein gradients play an important role in the spatial regulation of patterning during embryonic development. The most commonly accepted mechanism for gradient formation is diffusion from a source combined with degradation. Recently, there has… read more here.
Keywords: gradient formation; transport model; morphogen gradient; morphogen ... See more keywords
Robust boundary formation in a morphogen gradient via cell-cell signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Physical review. E"
DOI: 10.1103/physreve.105.064405
Abstract: Establishing sharp and correctly positioned boundaries in spatial gene expression patterns is a central task in both developmental and synthetic biology. We consider situations where a global morphogen gradient provides positional information to cells but… read more here.
Keywords: morphogen gradient; cell; boundary formation;