Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-23653-4
Abstract: Generating properly differentiated embryonic structures in vitro from pluripotent stem cells remains a challenge. Here we show that instruction of aggregates of mouse embryonic stem cells with an experimentally engineered morphogen signalling centre, that functions… read more here.
Keywords: signalling centre; mammalian embryo; morphogen signalling; stem ... See more keywords
Morphogen Signals Shaping the Gastric Glands in Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073632
Abstract: The adult gastric mucosa is characterised by deep invaginations of the epithelium called glands. These tissue architectural elements are maintained with the contribution of morphogen signals. Morphogens are expressed in specific areas of the tissue,… read more here.
Keywords: morphogen; morphogen signals; shaping gastric; gastric glands ... See more keywords