Articles with "morphogenetic protein" as a keyword



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Absorbable collagen sponges loaded with recombinant bone morphogenetic protein 9 induces greater osteoblast differentiation when compared to bone morphogenetic protein 2

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Published in 2017 at "Clinical and Experimental Dental Research"

DOI: 10.1002/cre2.55

Abstract: The use of growth factors for the regeneration of soft and hard tissues has been utilized extensively in dental medicine over the past decade. Recently our group found that recombinant human bone morphogenetic protein 9… read more here.

Keywords: osteoblast differentiation; rhbmp9; bone morphogenetic; morphogenetic protein ... See more keywords
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Bone morphogenetic protein‐2 incorporated calcium phosphate graft promotes peri‐implant bone defect healing in dogs: A pilot study

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Published in 2022 at "Clinical and Experimental Dental Research"

DOI: 10.1002/cre2.613

Abstract: The evaluation of three different drug delivery modes of bone morphogenetic protein‐2 (BMP‐2) in healing peri‐implant bone defects in beagle dogs. BMP‐2 was incorporated in or onto calcium phosphate (CaP) granules in various ways: (i)… read more here.

Keywords: bone; calcium phosphate; peri implant; bone morphogenetic ... See more keywords
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Lack of evidence that fibrillin1 regulates bone morphogenetic protein 4 activity in kidney or lung

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Published in 2023 at "Developmental Dynamics"

DOI: 10.1002/dvdy.578

Abstract: The Bone morphogenetic protein 4 (BMP4) precursor protein is cleaved at two sites to generate an active ligand and inactive prodomain. The ligand and prodomain form a noncovalent complex following the first cleavage, but dissociate… read more here.

Keywords: evidence fibrillin1; lack evidence; activity; bone morphogenetic ... See more keywords
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Characterization of new bone morphogenetic protein (Bmp)‐2 regulatory alleles

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Published in 2017 at "genesis"

DOI: 10.1002/dvg.23035

Abstract: Bone morphogenetic protein 2 (BMP2, HGNC:1069, GeneID: 650) is a classical morphogen; a molecule that acts at a distance and whose concentration influences cell proliferation, differentiation, and apoptosis. Key events requiring precise Bmp2 regulation include… read more here.

Keywords: bmp2; bone morphogenetic; morphogenetic protein; characterization new ... See more keywords
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Augmentation of bone morphogenetic protein signaling in cranial neural crest cells in mice deforms skull base due to premature fusion of intersphenoidal synchondrosis

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Published in 2023 at "genesis"

DOI: 10.1002/dvg.23509

Abstract: Craniofacial anomalies (CFAs) are a diverse group of disorders affecting the shapes of the face and the head. Malformation of the cranial base in humans leads CFAs, such as midfacial hypoplasia and craniosynostosis. These patients… read more here.

Keywords: premature fusion; fusion; morphogenetic protein; bone morphogenetic ... See more keywords
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Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole‐Exome Sequencing in a Patient with Delayed‐Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1R206H ‐Specific Human Cellular and Zebrafish Models

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Published in 2022 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.4711

Abstract: Bone morphogenetic protein (BMP) signaling is critical in skeletal development. Overactivation can trigger heterotopic ossification (HO) as in fibrodysplasia ossificans progressiva (FOP), a rare, progressive disease of massive HO formation. A small subset of FOP… read more here.

Keywords: protein bmp; bmp signaling; bone; bone morphogenetic ... See more keywords
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Association of plasma bone morphogenetic protein‐4 levels with arterial stiffness in hypertensive patients

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Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24746

Abstract: Arterial stiffness interacts with hypertension, becoming an early marker of hypertension‐mediated target organ damage. This study aimed to assess the association between plasma concentrations of bone morphogenetic protein‐4 (BMP‐4) and arterial stiffness during hypertension. read more here.

Keywords: morphogenetic protein; arterial stiffness; association plasma; bone morphogenetic ... See more keywords
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miR-149 promotes human osteocarcinoma progression via targeting bone morphogenetic protein 9 (BMP9)

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Published in 2017 at "Biotechnology Letters"

DOI: 10.1007/s10529-017-2445-8

Abstract: ObjectivesTo investigate the roles of miR-149 in the progression of human osteosarcoma (OS).ResultsmiR-149 level was upregulated in tissues from OS patients more than in normal subjects. Cell proliferation and apoptosis assays revealed that miR-149 increased… read more here.

Keywords: mg63 cells; mir 149; protein bmp9; bone morphogenetic ... See more keywords
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Fabrication and Characterization of Polyphosphazene/Calcium Phosphate Scaffolds Containing Chitosan Microspheres for Sustained Release of Bone Morphogenetic Protein 2 in Bone Tissue Engineering

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Published in 2017 at "Tissue Engineering and Regenerative Medicine"

DOI: 10.1007/s13770-017-0056-z

Abstract: Bone morphogenetic protein 2 has a major role in promoting bone regeneration in tissue engineering scaffolds. Growth factor release rate is a remaining crucial problem in these systems. The aim of this study was to… read more here.

Keywords: bone; bone morphogenetic; morphogenetic protein; tissue engineering ... See more keywords
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Boosting collagen deposition with a lysyl oxidase/bone morphogenetic protein-1 cocktail.

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Published in 2020 at "Methods in cell biology"

DOI: 10.1016/bs.mcb.2019.10.011

Abstract: This book chapter describes the use of exogenous application of lysyl oxidase (LOX) and bone morphogenetic protein-1 (BMP1) to enhance collagen synthesis and deposition from fibroblasts in culture. The protocol includes the generation of human… read more here.

Keywords: collagen; morphogenetic protein; bone morphogenetic; lysyl oxidase ... See more keywords
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Tuning the bioactivity of bone morphogenetic protein-2 with surface immobilization strategies.

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Published in 2018 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2018.09.011

Abstract: Bone morphogenetic protein-2 (BMP-2) involved therapy is of great potential for bone regeneration. However, its clinical application is restricted due to the undesirable bioactivity and relevant complications in vivo. Immobilization of recombinant BMP-2 (rhBMP-2) is… read more here.

Keywords: rhbmp; bioactivity; immobilization; bone ... See more keywords