Morphological intratumor heterogeneity in ductal carcinoma in situ of the breast
Sign Up to like & getrecommendations! Published in 2021 at "Virchows Archiv"
DOI: 10.1007/s00428-021-03040-6
Abstract: Ductal carcinoma in situ (DCIS) of the breast is a heterogeneous disease in terms of morphological characteristics, protein expression profiles, genetic abnormalities, and potential for progression. Molecular heterogeneity has been extensively studied in DCIS. Yet… read more here.
Keywords: carcinoma situ; heterogeneity; dcis; morphological intratumor ... See more keywords
A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei.
Sign Up to like & getrecommendations! Published in 2021 at "Nature protocols"
DOI: 10.1038/s41596-020-00432-x
Abstract: Cell morphology encodes essential information on many underlying biological processes. It is commonly used by clinicians and researchers in the study, diagnosis, prognosis, and treatment of human diseases. Quantification of cell morphology has seen tremendous… read more here.
Keywords: machine learning; robust unsupervised; unsupervised machine; morphological heterogeneity ... See more keywords
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence
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DOI: 10.3390/cancers13040895
Abstract: Simple Summary Pancreatic cancer has a poor prognosis, which is largely due to resistance to treatment. Tumor heterogeneity is a known cause for treatment failure and has been studied at the molecular level. Morphological heterogeneity… read more here.
Keywords: heterogeneity; pancreatic cancer; structural functional; cancer ... See more keywords