Inhibition of PCSK9 does not improve lipopolysaccharide-induced mortality in mice[S]
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DOI: 10.1194/jlr.m076844
Abstract: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protein that targets LDL receptors (LDLRs) for degradation in liver. Blocking the interaction of PCSK9 with the LDLR potently reduces plasma LDL cholesterol levels and cardiovascular… read more here.
Keywords: induced mortality; inhibition; pcsk9; mice ... See more keywords