Vaccine-driven virulence evolution: consequences of unbalanced reductions in mortality and transmission and implications for pertussis vaccines
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DOI: 10.1098/rsif.2019.0642
Abstract: Many vaccines have heterogeneous effects across individuals. Additionally, some vaccines do not prevent infection, but reduce disease-associated mortality and transmission. Both of these factors will alter selection pressures on pathogens and thus shape the evolution… read more here.
Keywords: virulence; virulence evolution; mortality transmission; evolution ... See more keywords