Computational and in vitro experimental analyses of the anti-COVID-19 potential of Mortaparib and MortaparibPlus
Sign Up to like & getrecommendations! Published in 2021 at "Bioscience Reports"
DOI: 10.1042/bsr20212156
Abstract: Abstract Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has become a global health emergency. Although new vaccines have been generated and being implicated, discovery and application of… read more here.
Keywords: vitro experimental; anti covid; mortaparib; mortaparib mortaparibplus ... See more keywords
Identification of a new member of Mortaparib class of inhibitors that target mortalin and PARP1
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.918970
Abstract: Mortalin, a heat shock family protein enriched in cancer cells, is known to inactivate tumor suppressor protein p53. Abrogation of mortalin-p53 interaction and reactivation of p53 has been shown to trigger growth arrest/apoptosis in cancer… read more here.
Keywords: compound; mortaparib; p53; mortalin parp1 ... See more keywords