Chromosomal mosaicism in human blastocysts: the ultimate challenge of preimplantation genetic testing?
Sign Up to like & getrecommendations! Published in 2018 at "Human Reproduction"
DOI: 10.1093/humrep/dey106
Abstract: STUDY QUESTION To what extent does a trophectoderm (TE) biopsy reliably reflect the chromosomal constitution of the inner cell mass (ICM) in human blastocysts? SUMMARY ANSWER Concordance between TE and ICM was established in 62.1%… read more here.
Keywords: mosaicism; group; chromosomal mosaicism; mosaicism human ... See more keywords
The human brain through the lens of somatic mosaicism
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1172469
Abstract: Every cell in the human brain possesses a unique genome that is the product of the accumulation of somatic mutations starting from the first postzygotic cell division and continuing throughout life. Somatic mosaicism in the… read more here.
Keywords: cell; mosaicism human; brain; human brain ... See more keywords