Strand-like structures and the nonstructural proteins 5, 3 and 1 are present in the nucleus of mosquito cells infected with dengue virus.
Sign Up to like & getrecommendations! Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2017.12.014
Abstract: Dengue virus (DENV) is an arbovirus, which replicates in the endoplasmic reticulum. Although replicative cycle takes place in the cytoplasm, some viral proteins such as NS5 and C are translocated to the nucleus during infection… read more here.
Keywords: dengue virus; strand like; like structures; mosquito cells ... See more keywords
Extracellular vesicles restrict dengue virus fusion in Aedes aegypti cells.
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DOI: 10.1016/j.virol.2019.12.010
Abstract: Aedes aegypti is the primary vector of dengue virus (DENV), and acquires this virus from a vertebrate host during blood feeding. Previous literature has shown that vertebrate blood factors such as complement protein C5a and… read more here.
Keywords: extracellular vesicles; dengue virus; aedes aegypti; mosquito cells ... See more keywords
The Dengue Virus Nonstructural Protein 1 (NS1) Is Secreted from Mosquito Cells in Association with the Intracellular Cholesterol Transporter Chaperone Caveolin Complex
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.01985-18
Abstract: The dengue virus protein NS1 is secreted efficiently from both infected vertebrate and mosquito cells. Previously, our group reported that NS1 secretion in mosquito cells follows an unconventional secretion pathway dependent on caveolin-1. In this… read more here.
Keywords: mosquito; secretion; chaperone caveolin; caveolin complex ... See more keywords
Insect-Specific Chimeric Viruses Potentiated Antiviral Responses and Inhibited Pathogenic Alphavirus Growth in Mosquito Cells
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DOI: 10.1128/spectrum.03613-22
Abstract: Mosquito-borne alphaviruses can cause emerging and reemerging infectious diseases, posing a considerable threat to human and animal health worldwide. However, no specific antivirals or commercial vaccines are currently available. ABSTRACT Most alphaviruses are transmitted by… read more here.
Keywords: pathogenic alphavirus; mosquito cells; chimeric viruses; insect specific ... See more keywords
XBP1-Mediated BiP/GRP78 Upregulation Copes with Oxidative Stress in Mosquito Cells during Dengue 2 Virus Infection
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DOI: 10.1155/2017/3519158
Abstract: Dengue viruses (DENVs) cause dengue fever which is an important mosquito-borne disease in tropical areas. Generally, DENV does not cause cellular damage in mosquito cells. However, alterations in cytosolic calcium ions ([Ca2+]cyt) and the mitochondrial… read more here.
Keywords: mosquito; bip grp78; oxidative stress; infection ... See more keywords
Chikungunya virus entry and infectivity is primarily facilitated through cell line dependent attachment factors in mammalian and mosquito cells
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DOI: 10.3389/fcell.2023.1085913
Abstract: Chikungunya virus (CHIKV) is the causative agent of the human disease chikungunya fever, characterized by debilitating acute and chronic arthralgia. No licensed vaccines or antivirals are currently available for CHIKV. Therefore, the prevention of attachment… read more here.
Keywords: mammalian mosquito; entry; cell line; mosquito cells ... See more keywords
PERK Signal-Modulated Protein Translation Promotes the Survivability of Dengue 2 Virus-Infected Mosquito Cells and Extends Viral Replication
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DOI: 10.3390/v9090262
Abstract: Survival of mosquitoes from dengue virus (DENV) infection is a prerequisite of viral transmission to the host. This study aimed to see how mosquito cells can survive the infection during prosperous replication of the virus.… read more here.
Keywords: translation; protein translation; mosquito cells; perk signal ... See more keywords