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   Articles with "mother centriole" as a keyword



M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole

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recommendations! Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-06990-9

Abstract: The primary cilium is elongated from the mother centriole and has diverse signaling roles during development and disease. The CP110-CEP97 complex functions as a negative regulator of ciliogenesis, although the mechanisms regulating its mother centriole… read more here.

Keywords: ciliogenesis; localization; mother centriole; cp110 cep97 ... See more keywords

Mutually independent and cilia-independent assembly of IFT-A and IFT-B complexes at mother centriole

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recommendations! Published in 2025 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e24-11-0509

Abstract: The intraflagellar transport (IFT) machinery, containing the IFT-A and IFT-B complexes and powered by dynein-2 and kinesin-2 motors, is crucial for bidirectional trafficking of ciliary proteins and their import/export across the transition zone (TZ). Stepwise… read more here.

Keywords: ift ift; ift complexes; mother centriole; centriole mutually ... See more keywords

Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis

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recommendations! Published in 2022 at "eLife"

DOI: 10.1101/2022.04.04.486992

Abstract: Centrosomes are orbited by centriolar satellites, dynamic multiprotein assemblies nucleated by PCM1. To study the requirement for centriolar satellites, we generated mice lacking PCM1. Pcm1−/− mice display partially penetrant perinatal lethality with survivors exhibiting hydrocephalus,… read more here.

Keywords: ciliogenesis; centriolar satellites; mother centriole; expedite mother ... See more keywords

EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole.

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recommendations! Published in 2023 at "EMBO reports"

DOI: 10.15252/embr.202256317

Abstract: Primary cilia are sensory organelles that coordinate diverse signaling pathways, controlling development and homeostasis. Progression beyond the early steps of ciliogenesis requires the removal of a distal end protein, CP110, from the mother centriole, a… read more here.

Keywords: herc2; ciliogenesis; mother centriole; cp110 ubiquitination ... See more keywords