Targeting a KRAS i‐motif forming sequence by unmodified and gamma‐modified peptide nucleic acid oligomers
Sign Up to like & getrecommendations! Published in 2022 at "Biopolymers"
DOI: 10.1002/bip.23529
Abstract: Growing interest in i‐motif DNA as a transcriptional regulatory element motivates development of synthetic molecules capable of targeting these structures. In this study, we designed unmodified peptide nucleic acid (PNA) and gamma‐modified PNA (γPNA) oligomers… read more here.
Keywords: spectroscopy; motif forming; pna pna; sequence ... See more keywords
GCTTCA as a novel motif for regulating mesocarp-specific expression of the oil palm (Elaeis guineensis Jacq.) stearoyl-ACP desaturase gene
Sign Up to like & getrecommendations! Published in 2018 at "Plant Cell Reports"
DOI: 10.1007/s00299-018-2300-y
Abstract: Key messageTAAAAT and a novel motif, GCTTCA found in the oil palm stearoyl-ACP desaturase (SAD1) promoter are involved in regulating mesocarp-specific expression.AbstractTwo key fatty acid biosynthetic genes, stearoyl-ACP desaturase (SAD1), and acyl-carrier protein (ACP3) in… read more here.
Keywords: novel motif; motif; mesocarp; oil palm ... See more keywords
Characterization of two cis-acting elements, P1BS and W-box, in the regulation of OsPT6 responsive to phosphors deficiency
Sign Up to like & getrecommendations! Published in 2021 at "Plant Growth Regulation"
DOI: 10.1007/s10725-020-00688-z
Abstract: Phosphorus (P) deficiency is one of the major nutrient stresses restricting plant growth. The uptake of P by plants from soil is mainly mediated by the phosphate (Pi) transporters belonging to the PHT1 family. Multiple… read more here.
Keywords: starvation; regulation; box; promoter ... See more keywords
Properties of Calmodulin Binding to NaV1.2 IQ Motif and Its Autism-Associated Mutation R1902C.
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical research"
DOI: 10.1007/s11064-020-03189-7
Abstract: Voltage-gated sodium channels (VGSCs) are fundamental to the initiation and propagation of action potentials in excitable cells. Ca2+/calmodulin (CaM) binds to VGSC type II (NaV1.2) isoleucine and glutamine (IQ) motif. An autism-associated mutation in NaV1.2… read more here.
Keywords: cam; motif; autism associated; nav1 motif ... See more keywords
Oscillator Motif as Design Pattern for the Spinal Cord Circuitry Reconstruction
Sign Up to like & getrecommendations! Published in 2020 at "BioNanoScience"
DOI: 10.1007/s12668-020-00743-z
Abstract: This work is dedicated to the reverse engineering of the basic circuit motif of more complicated neural networks in the central nervous system (CNS). In this work, we introduce and evaluate a new approach to… read more here.
Keywords: motif design; motif; design pattern; pattern spinal ... See more keywords
Molecular details of the Raptor-binding motif on Arabidopsis S6 kinase.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.03.013
Abstract: A putative raptor-binding fragment was identified from Arabidopsis S6 kinase 1 (AtS6K1) N-terminal domain in our previous study. Here, we report a further characterization of this fragment, which identified a 12-amino acid core element absolutely… read more here.
Keywords: tos motif; arabidopsis kinase; motif; kinase ... See more keywords
Crystal structure of a novel RNA motif that allows for precise positioning of a single metal ion.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2017.08.029
Abstract: We have determined a crystal structure of an RNA duplex containing a novel metal-binding motif. The motif is composed of two sheared G○A base pairs, two unpaired A residues and four phosphate groups in close… read more here.
Keywords: crystal structure; motif; allows precise; metal ... See more keywords
Buffer effects on site directed Cu2+-labeling using the double histidine motif.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of magnetic resonance"
DOI: 10.1016/j.jmr.2020.106848
Abstract: The double histidine, or dHis, motif has emerged as a powerful spin labeling tool to determine the conformations and dynamics, subunit orientation, native metal binding site location, and other physical characteristics of proteins by Cu2+-based… read more here.
Keywords: motif; double histidine; site; cu2 nta ... See more keywords
Synthesis of organic motif tailored hybrid nanoframes: Exploiting in vitro bioactivity and heavy metal ion extraction applications
Sign Up to like & getrecommendations! Published in 2017 at "Materials Chemistry and Physics"
DOI: 10.1016/j.matchemphys.2016.12.034
Abstract: Abstract Hybrid nanoparticles (NPs) were designed by adsorbing a (13E,19E)-N1′,N3′-bis[4-(diethylamino)-2-hydroxybenzylidene]malonohydrazide (L) motif, on Fe3O4@SiO2 distorted hexagonal and cubic NPs. Electronic images of the synthesized hybrid NPs revealed distorted topographies with size of ∼50–70 nm. We exploited… read more here.
Keywords: motif; ion extraction; ion; metal ion ... See more keywords
Switchable Multiplex Photoelectrochemical Immunoassay of Aβ42 and Aβ40 Based on a pH-Responsive i-Motif Probe and Pyrene-Based MOF Photocathode.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01142
Abstract: In accurately diagnosing Alzheimer's disease (AD) and distinguishing AD from other dementia, the concentration ratio of amyloid-beta 42 (Aβ42) to Aβ40 is more reliable than the concentration of Aβ42 alone. For the multiplex PEC assay,… read more here.
Keywords: motif; switchable multiplex; photocathode; single interface ... See more keywords
Accurate and Efficient Determination of Unknown Metabolites in Metabolomics by NMR-Based Molecular Motif Identification.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b03849
Abstract: Knowledge of the chemical identity of metabolite molecules is critical for the understanding of the complex biological systems they belong to. Since metabolite identities and their concentrations are often directly linked to the phenotype, such… read more here.
Keywords: chemical shifts; motif; structural motifs; unknown metabolites ... See more keywords