Articles with "motif containing" as a keyword



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Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.

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Published in 2021 at "Cell and tissue research"

DOI: 10.1007/s00441-021-03518-4

Abstract: Tripartite motif-containing protein (TRIM16) is a newly identified oxidative-stress-responsive protein. Oxidative stress is a hallmark of myocardial ischemia/reperfusion (I/R) injury and contributes to the cardiac injury. To date, whether TRIM16 plays a role in mediating… read more here.

Keywords: protein; myocardial injury; tripartite motif; motif containing ... See more keywords
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Cloning, analysis, and anti–duck Tembusu virus innate immune response of Cherry Valley duck tripartite motif-containing 32

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Published in 2021 at "Poultry Science"

DOI: 10.1016/j.psj.2021.101048

Abstract: Tripartite motif-containing 32 (TRIM32) is an E3 ubiquitin ligase with multiple functions. In this study, we amplified TRIM32 gene from the Cherry Valley duck, and its cDNA sequence contained an open reading frame of 1,950… read more here.

Keywords: response; duck; tripartite motif; cherry valley ... See more keywords
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Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1.

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Published in 2020 at "Biochemistry"

DOI: 10.1021/acs.biochem.9b01078

Abstract: Sterile alpha and toll/interleukin receptor (TIR) motif-containing protein 1 (SARM1) plays a pivotal role in triggering the neurodegenerative processes that underlie peripheral neuropathies, traumatic brain injury, and neurodegenerative diseases. Importantly, SARM1 knock down or knock… read more here.

Keywords: alpha toll; toll interleukin; motif containing; interleukin receptor ... See more keywords

IQ motif-containing GTPase-activating protein 1 is essential for the optimal maintenance of lung ILC2s.

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Published in 2019 at "International immunology"

DOI: 10.1093/intimm/dxz077

Abstract: Group 2 innate lymphoid cells (ILC2s) play critical roles in type 2 immunity and are crucial for pathogenesis of various types of inflammatory disease. IQ motif-containing GTPase-activating protein 1 (IQGAP1) is a ubiquitously expressed scaffold… read more here.

Keywords: lung ilc2s; containing gtpase; gtpase activating; ilc2s ... See more keywords

P0024TRIPARTITE MOTIF-CONTAINING 55 (TRIM55) PARTICIPATES IN THE IMMUNE RESPONSE IN THE EXPERIMENTAL ANTI-THY1 GLOMERULONEPHRITIS

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Published in 2020 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaa142.p0024

Abstract: Mesangial proliferative glomerulonephritis (MsPGN) is considered as an immune- related disease. In the previous study, tripartite motif family was reported to be closely related to immune regulation. Therefore, we performed a series of experiments in… read more here.

Keywords: trim55; primary rmcs; anti thy1; motif containing ... See more keywords

Deficiency of IQCH causes male infertility in humans and mice

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Published in 2024 at "eLife"

DOI: 10.1101/2023.06.23.546221

Abstract: IQ motif-containing proteins can be recognized by calmodulin (CaM) and are essential for many biological processes. However, the role of IQ motif-containing proteins in spermatogenesis is largely unknown. In this study, we identified a loss-of-function… read more here.

Keywords: containing proteins; male infertility; motif containing; iqch ... See more keywords

Tripartite motif‐containing proteins precisely and positively affect host antiviral immune response

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Published in 2018 at "Scandinavian Journal of Immunology"

DOI: 10.1111/sji.12669

Abstract: The tripartite motif‐containing proteins (TRIMs) comprise a large family of proteins with over 70 members in humans. Recent studies have shown that TRIMs play unexpected roles in the antiviral immune responses to infections by HIV,… read more here.

Keywords: containing proteins; tripartite motif; motif containing; host ... See more keywords

Tripartite motif-containing protein 21 is involved in IFN-γ-induced suppression of hepatitis B virus by regulating hepatocyte nuclear factors

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Published in 2024 at "Journal of Virology"

DOI: 10.1128/jvi.00468-24

Abstract: ABSTRACT The antiviral role of the tripartite motif-containing (TRIM) protein family , a member of the E3-ubiquitin ligase family, has recently been actively studied. Hepatitis B virus (HBV) infection is a major contributor to liver… read more here.

Keywords: hbv; hepatitis virus; tripartite motif; motif containing ... See more keywords

E3 ubiquitin ligase tripartite motif-containing 71 promotes the proliferation of non-small cell lung cancer through the inhibitor of kappaB-α/nuclear factor kappaB pathway

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Published in 2018 at "Oncotarget"

DOI: 10.18632/oncotarget.19075

Abstract: Tripartite motif-containing (TRIM) 71 belongs to the TRIM protein family. Many studies have shown that TRIM71 plays conserved roles in stem cell proliferation, differentiation, and embryonic development; however, the relationship between TRIM71 and tumorigenesis is… read more here.

Keywords: proliferation; tripartite motif; motif containing; non small ... See more keywords

Tripartite Motif-containing 22 Is Involved in TLR3-mediated Inflammatory Pathway in Rheumatoid Fibroblast-like Synoviocytes

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Published in 2025 at "In Vivo"

DOI: 10.21873/invivo.14123

Abstract: Background/Aim: Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation and cartilage destruction. Tripartite motif-containing 22 (TRIM22) is involved in intracellular signal transduction, protein regulation, and innate immunity through E3 ubiquitin ligase activity.… read more here.

Keywords: fibroblast like; tripartite motif; motif containing; trim22 ... See more keywords

PlantEAR: Functional Analysis Platform for Plant EAR Motif-Containing Proteins

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Published in 2018 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2018.00590

Abstract: The Ethylene-responsive element binding factor-associated Amphiphilic Repression (EAR) motifs, which were initially identified in members of the Arabidopsis ethylene response factor (ERF) family, are transcriptional repression motifs in plants and are defined by the consensus… read more here.

Keywords: containing proteins; plant; analysis; motif containing ... See more keywords