Articles with "motif novel" as a keyword



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Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitors

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Published in 2022 at "Frontiers in Chemistry"

DOI: 10.3389/fchem.2022.1078163

Abstract: A series of pyrazolyl-s-triazine compounds with an indole motif was designed, synthesized, and evaluated for anticancer activity targeting dual EGFR and CDK-2 inhibitors. The compounds were tested for cytotoxicity using the MTT assay. Compounds 3h,… read more here.

Keywords: pyrazolyl triazine; motif novel; indole motif; novel epidermal ... See more keywords