A transposon‐introduced G‐quadruplex motif is selectively retained and constrained to downregulate CYP321A1
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DOI: 10.1111/1744-7917.13021
Abstract: Insects utilize xenobiotic compounds to up‐ and downregulate cytochrome P450 monooxygenases (P450s) involved in detoxification of toxic xenobiotics including phytochemicals and pesticides. G‐quadruplexes (G4)‐forming DNA motifs are enriched in the promoter regions of transcription factors… read more here.
Keywords: dna; dna motif; cyp321a1; motif selectively ... See more keywords