Ghrelin and Motilin Control Systems in GI Physiology and Therapeutics.
Sign Up to like & getrecommendations! Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2016_104
Abstract: Ghrelin and motilin are released from gastrointestinal endocrine cells during hunger, to act through G protein-coupled receptors that have closely related amino acid sequences. The actions of ghrelin are more complex than motilin because ghrelin… read more here.
Keywords: motilin; ghrelin receptor; ghrelin motilin; physiology ... See more keywords
Biosynthesis, Chemical Synthesis, and Pharmacological Evaluation of Lyngbyapeptin A as a GPCR Antagonist of Motilin, Cannabinoid, and Amylin Receptors.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.5c00963
Abstract: Lyngbyapeptin A (1) is a linear modified tetrapeptide originally isolated from the marine cyanobacterium Moorena bouillonii in Papua New Guinea and Guam. In previous research, 1 did not show significant cytotoxicity but was not rigorously… read more here.
Keywords: motilin; chemical synthesis; biosynthesis chemical; cannabinoid ... See more keywords
The Mechanism of Action of Ghrelin and Motilin in the Pacemaker Potentials of Interstitial Cells of Cajal from the Murine Small Intestine
Sign Up to like & getrecommendations! Published in 2019 at "Molecules and Cells"
DOI: 10.14348/molcells.2019.0028
Abstract: Interstitial cells of Cajal (ICCs) are pacemaker cells that exhibit periodic spontaneous depolarization in the gastrointestinal (GI) tract and generate pacemaker potentials. In this study, we investigated the effects of ghrelin and motilin on the… read more here.
Keywords: motilin; pacemaker; pacemaker potentials; small intestine ... See more keywords
Motilin and its receptor are expressed in the dorsal horn in a rat model of acute incisional pain: Intrathecal motilin injection alleviates pain behaviors
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1104862
Abstract: Aims To observe the effects of intrathecal administration of motilin on pain behavior and expression of motilin (MTL)/motilin receptor (MTLR) in the spinal cord of a rat model of acute incisional pain. Methods An incisional… read more here.
Keywords: motilin; motilin receptor; incisional pain; pain ... See more keywords
Motilin, a Novel Orexigenic Factor, Involved in Feeding Regulation in Yangtze Sturgeon (Acipenser dabryanus)
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DOI: 10.3390/biom14040433
Abstract: Motilin is a gastrointestinal hormone that is mainly produced in the duodenum of mammals, and it is responsible for regulating appetite. However, the role and expression of motilin are poorly understood during starvation and the… read more here.
Keywords: acipenser dabryanus; motilin; brain; yangtze sturgeon ... See more keywords
Gut Hormones as Potential Therapeutic Targets or Biomarkers of Response in Depression: The Case of Motilin
Sign Up to like & getrecommendations! Published in 2021 at "Life"
DOI: 10.3390/life11090892
Abstract: Recent research has identified the gut–brain axis as a key mechanistic pathway and potential therapeutic target in depression. In this paper, the potential role of gut hormones as potential treatments or predictors of response in… read more here.
Keywords: motilin; depression; gut hormones; hormones potential ... See more keywords