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Published in 2017 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24125
Abstract: Cervical spinal hemisection at C2 (SH) removes premotor drive to phrenic motoneurons located in segments C3–C5 in rats. Spontaneous recovery of ipsilateral diaphragm muscle activity is associated with increased phrenic motoneuron expression of glutamatergic N‐methyl‐D‐aspartate…
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Keywords:
motoneuron;
recovery;
glutamatergic;
receptor expression ... See more keywords
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Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.10.005
Abstract: When facial nerve axotomy (FNA) is performed on immunodeficient recombinase activating gene-2 knockout (RAG-2-/-) mice, there is greater facial motoneuron (FMN) death relative to wild type (WT) mice. Reconstituting RAG-2-/- mice with whole splenocytes rescues…
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Keywords:
motoneuron;
death;
whole splenocytes;
mice ... See more keywords
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Published in 2021 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2021.08.006
Abstract: OBJECTIVE Only few studies investigated voluntary movement abnormalities in patients with motoneuron diseases (MNDs) or their neurophysiological correlates. We aimed to kinematically assess finger tapping abnormalities in patients with amyotrophic lateral sclerosis (ALS) and primary…
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Keywords:
motoneuron;
movement;
movement slowness;
finger tapping ... See more keywords
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Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.03.051
Abstract: Transverse sections of the monkey cervical spinal cord from a previous study (Jenny and Inukai, 1983) were reanalyzed using Neurolucida to create a three-dimensional display of extensor digitorum communis (EDC) motoneurons and proximal dendrites that…
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Keywords:
motoneuron;
small motoneurons;
digitorum communis;
extensor digitorum ... See more keywords
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Published in 2022 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2022.3232067
Abstract: Objective: Robust neural decoding of intended motor output is crucial to enable intuitive control of assistive devices, such as robotic hands, to perform daily tasks. Few existing neural decoders can predict kinetic and kinematic variables…
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Keywords:
finger;
kinematics;
motoneuron;
prediction ... See more keywords
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Published in 2020 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00529.2020
Abstract: Nerve transfers (neurotizations) performed under optimal conditions can restore some voluntary control in muscles of the upper extremities in patients with tetraplegia. However, the type of motoneuron lesions in target muscles for nerve transfers influences…
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Keywords:
motoneuron;
nerve transfer;
lower motor;
motor ... See more keywords
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Published in 2018 at "Journal of neurophysiology"
DOI: 10.1152/jn.00068.2018
Abstract: Cat lumbar motoneurons display changes in membrane properties during fictive locomotion. These changes include reduction of input resistance and afterhyperpolarization, hyperpolarization of voltage threshold, and voltage-dependent excitation of the motoneurons. The state-dependent alteration of membrane…
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Keywords:
motoneuron;
fictive locomotion;
locomotion;
output ... See more keywords
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Published in 2022 at "Journal of neurophysiology"
DOI: 10.1152/jn.00336.2022
Abstract: It has been shown that when humans lean in various directions, the central nervous system (CNS) recruits different motoneuron pools for task completion; common units that are active during different leaning directions, and unique units…
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Keywords:
motoneuron pools;
motoneuron;
leaning directions;
leaning direction ... See more keywords
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Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1010556
Abstract: Our understanding of the firing behaviour of motoneuron (MN) pools during human voluntary muscle contractions is currently limited to electrophysiological findings from animal experiments extrapolated to humans, mathematical models of MN pools not validated for…
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Keywords:
firing behaviour;
firing activity;
motoneuron;
muscle ... See more keywords
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Published in 2018 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00431
Abstract: Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder with no effective treatment currently available. Although the mechanisms of motoneuron (MN) death are still unclear, glutamate excitotoxicity and neuroinflammatory reaction are two main features in…
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Keywords:
motoneuron;
death;
neuregulin reduces;
vitro model ... See more keywords
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Published in 2020 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2020.00074
Abstract: The most evident phenotype of degenerative motoneuron disease is the loss of motor function which accompanies motoneuron death. In both amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), it is now clear that dysfunction…
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Keywords:
motoneuron;
motoneuron disease;
disease;
motoneuronal spinal ... See more keywords