Factors associated with motor complications in Parkinson's disease
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DOI: 10.1002/brb3.837
Abstract: Levodopa is the most effective therapy for treating Parkinson's disease (PD); however, side effects such as dyskinesias and motor fluctuations may occur after some years of its usage. The aims of this study were to… read more here.
Keywords: motor complications; factors associated; complications parkinson; motor ... See more keywords
Levodopa: A new look at an old friend
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DOI: 10.1002/mds.27216
Abstract: Levodopa is the most effective antiparkinsonian agent, but chronic treatment is associated with the development of motor complications in the majority of patients with PD. Recent scientific and clinical advances are improving this situation. Long‐term,… read more here.
Keywords: look old; motor complications; levodopa new; new look ... See more keywords
Motor complications in Parkinson's disease: 13‐year follow‐up of the CamPaIGN cohort
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DOI: 10.1002/mds.27882
Abstract: Long‐term population‐representative data on motor fluctuations and levodopa‐induced dyskinesias in Parkinson's disease is lacking. read more here.
Keywords: motor complications; year follow; complications parkinson; disease year ... See more keywords
Benign versus malignant Parkinson disease: the unexpected silver lining of motor complications
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DOI: 10.1007/s00415-020-09954-6
Abstract: Objective We sought to evaluate demographic, clinical, and habits/occupational variables between phenotypic extremes in Parkinson’s disease (PD). Methods Databases from nine movement disorders centers across seven countries were retrospectively searched for subjects meeting criteria for… read more here.
Keywords: motor complications; habits occupational; parkinson disease; mpd ... See more keywords
Risk factors for motor complications in female patients with Parkinson’s disease
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DOI: 10.1007/s10072-022-05959-3
Abstract: To investigate the risk factors of motor complications in female patients with Parkinson’s disease (PD) and the correlation between the occurrence of motor complications and sex hormone levels. According to the occurrence and types of… read more here.
Keywords: motor complications; wearing phenomenon; female patients; risk factors ... See more keywords
New dopaminergic therapies for PD motor complications
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DOI: 10.1016/j.neuropharm.2021.108869
Abstract: BACKGROUND Motor complications, characterized by "off" periods - when anti-parkinsonian medications are ineffective - and dyskinesia, are the hallmark of advanced Parkinson's disease (PD). While levodopa is the gold standard PD medication in terms of… read more here.
Keywords: motor complications; new dopaminergic; dopaminergic therapies; motor ... See more keywords
Recent Advances in Drug Therapy for Parkinson's Disease
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DOI: 10.2169/internalmedicine.8940-21
Abstract: Parkinson's disease (PD) is a neurodegenerative disease manifesting with motor and non-motor symptoms. Current treatment mainly relies on medication as a symptomatic therapy modulating neurotransmitters. Dopamine replacement therapy has been established, and levodopa is the… read more here.
Keywords: disease; parkinson disease; therapy; motor complications ... See more keywords
Chronological View of Peak and Diphasic Dyskinesia, Wearing Off and Freezing of Gait in Parkinson's Disease.
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DOI: 10.3233/jpd-191624
Abstract: BACKGROUND Dyskinesia, wearing off (WO) and freezing of gait (FOG) are troublesome complications degrading quality of life in the course of Parkinson's disease (PD). OBJECTIVE This study evaluated the gross chronological trend of 4 motor… read more here.
Keywords: parkinson disease; motor complications; dyskinesia; dyskinesia wearing ... See more keywords
Pharmacokinetics of Levodopa and 3-O-Methyldopa in Parkinsonian Patients Treated with Levodopa and Ropinirole and in Patients with Motor Complications
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DOI: 10.3390/pharmaceutics13091395
Abstract: Parkinson’s disease (PD) is a progressive, neurodegenerative disorder primarily affecting dopaminergic neuronal systems, with impaired motor function as a consequence. The most effective treatment for PD remains the administration of oral levodopa (LD). Long-term LD… read more here.
Keywords: motor complications; ropinirole patients; patients treated; patients motor ... See more keywords