How different aspects of motor dysfunction influence day‐to‐day function in huntington's disease
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders"
DOI: 10.1002/mds.27866
Abstract: This study examined the relationships between different aspects of motor dysfunction (chorea, dystonia, rigidity, incoordination, oculomotor dysfunction, dysarthria, and gait difficulties) and functional status in persons with Huntington's disease. read more here.
Keywords: aspects motor; huntington disease; dysfunction; different aspects ... See more keywords
Programmed Death-1 Deficiency Aggravates Motor Dysfunction in MPTP Model of Parkinson's Disease by Inducing Microglial Activation and Neuroinflammation in Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular neurobiology"
DOI: 10.1007/s12035-022-02758-x
Abstract: Abundant reactive gliosis and neuroinflammation are typical pathogenetic hallmarks of brains in Parkinson's disease (PD) patients, but regulation mechanisms are poorly understood. We are interested in role of programmed death-1 (PD-1) in glial reaction, neuroinflammation… read more here.
Keywords: mptp; motor dysfunction; model; neuroinflammation ... See more keywords
Motor function deficits in the 12 month-old female 5xFAD mouse model of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.09.009
Abstract: Abstract Motor problems occur early in some patients with Alzheimer’s disease (AD) and as the disease progresses many patients develop motor dysfunction. Motor dysfunction has been reported in some mouse models of AD, including the… read more here.
Keywords: disease; 5xfad mice; motor; mice ... See more keywords
Vitamin D supplementation has no effects on progression of motor dysfunction in amyotrophic lateral sclerosis (ALS)
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Clinical Nutrition"
DOI: 10.1038/s41430-019-0448-3
Abstract: Objectives To investigate the effects of cholecalciferol supplementation on the progression of motor disability in a cohort of amyotrophic lateral sclerosis (ALS) patients with low blood 25-hydroxyvitamin D3 [25(OH)D] levels, on the basis of the… read more here.
Keywords: 000 month; supplementation; motor; motor dysfunction ... See more keywords
Ameliorating parkinsonian motor dysfunction by targeting histamine receptors in entopeduncular nucleus-thalamus circuitry.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2216247120
Abstract: In Parkinson's disease (PD), reduced dopamine levels in the basal ganglia have been associated with altered neuronal firing and motor dysfunction. It remains unclear whether the altered firing rate or pattern of basal ganglia neurons… read more here.
Keywords: parkinsonism associated; motor; associated motor; motor dysfunction ... See more keywords
Theta burst stimulation for upper limb motor dysfunction in patients with stroke
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000017929
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: limb motor; stimulation upper; burst stimulation; theta burst ... See more keywords
Rovatirelin ameliorates motor dysfunction in the cytosine arabinoside‐induced rat model of spinocerebellar degeneration via acetylcholine and dopamine neurotransmission
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13675
Abstract: Thyrotropin‐releasing hormone (TRH) and the TRH mimetic taltirelin have been used in Japan for the treatment of spinocerebellar degeneration (SCD), a type of progressive ataxia. A TRH mimetic, rovatirelin, ameliorates ataxia symptoms in the rolling… read more here.
Keywords: rovatirelin ameliorates; motor dysfunction; motor; model ... See more keywords
Age‐related deterioration of motor function in male and female 5xFAD mice from 3 to 16 months of age
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.1111/gbb.12538
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder that leads to age‐related cognitive and sensori‐motor dysfunction. There is an increased understanding that motor dysfunction contributes to overall AD severity, and a need to ameliorate these impairments.… read more here.
Keywords: age; 5xfad mice; motor; motor dysfunction ... See more keywords
Dysphagia in amyotrophic lateral sclerosis: Quantification of bulbar motor dysfunction.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of oral rehabilitation"
DOI: 10.1111/joor.13220
Abstract: BACKGROUND Dysphagia as a sequel and possible early sign of amyotrophic lateral sclerosis (ALS) is caused by progressive impaired bulbar motor function. OBJECTIVE To evaluate bulbar motor dysfunction in patients suffering from ALS compared to… read more here.
Keywords: dysphagia; bulbar motor; motor dysfunction;
Electroacupuncture as an adjunctive therapy for motor dysfunction in acute stroke survivors: a systematic review and meta-analyses
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Open"
DOI: 10.1136/bmjopen-2017-017153
Abstract: Objectives To assess the effectiveness and safety of electroacupuncture (EA) combined with rehabilitation therapy (RT) and/or conventional drugs (CD) for improving poststroke motor dysfunction (PSMD). Design Systematic review and meta-analysis. Methods The China National Knowledge… read more here.
Keywords: review meta; systematic review; meta; therapy ... See more keywords
Animal models of developmental motor disorders: parallels to human motor dysfunction in cerebral palsy.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neurophysiology"
DOI: 10.1152/jn.00233.2019
Abstract: Cerebral palsy (CP) is the most common motor disability in children. Much of the previous research on CP has focused on reducing the severity of brain injuries, while very few researchers investigate the cause and… read more here.
Keywords: cerebral palsy; animal models; motor; motor dysfunction ... See more keywords