Analysing single-molecule trajectories to reconstruct free-energy landscapes of cyclic motor proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.11.015
Abstract: Stochastic trajectories measured in single-molecule experiments have provided key insights into the microscopic behaviour of cyclic motor proteins. However, the fundamental free-energy landscapes of motor proteins are currently only able to be determined by computationally… read more here.
Keywords: cyclic motor; energy landscapes; single molecule; motor proteins ... See more keywords
Molecular Assembly of Rotary and Linear Motor Proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.9b00015
Abstract: Molecular machines are an important and emerging frontier in research encompassing interdisciplinary subjects of chemistry, physics, biology, and nanotechnology. Although there has been major interest in creating synthetic molecular machines, research on natural molecular machines… read more here.
Keywords: motor proteins; chemistry; biomolecular motor; molecular machines ... See more keywords
Computational modeling of dynein motor proteins at work.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc05857b
Abstract: Along with various experimental methods, a combination of theoretical and computational methods is essential to explore different length-scale and time-scale processes in the biological system. The functional mechanism of a dynein, an ATP-fueled motor protein,… read more here.
Keywords: motor proteins; computational modeling; mechanochemical cycle; dynein ... See more keywords
Cooperation and competition in the collective drive by motor proteins: mean active force, fluctuations, and self-load.
Sign Up to like & getrecommendations! Published in 2022 at "Soft matter"
DOI: 10.1039/d2sm01183b
Abstract: We consider the dynamics of a bio-filament under the collective drive of motor proteins. They are attached irreversibly to a substrate and undergo stochastic attachment-detachment with the filament to produce a directed force on it.… read more here.
Keywords: drive motor; collective drive; motor; force ... See more keywords
Understanding protein translocation across chloroplast membranes: translocons and motor proteins.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of integrative plant biology"
DOI: 10.1111/jipb.13385
Abstract: Subcellular organelles in eukaryotes are surrounded by lipid membranes. In an endomembrane system, vesicle trafficking is the primary mechanism for the delivery of organellar proteins to specific organelles. However, organellar proteins for chloroplasts, mitochondria, the… read more here.
Keywords: chloroplast; tic complexes; toc tic; understanding protein ... See more keywords
Simulated actin reorganization mediated by motor proteins
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1010026
Abstract: Cortical actin networks are highly dynamic and play critical roles in shaping the mechanical properties of cells. The actin cytoskeleton undergoes significant reorganization in many different contexts, including during directed cell migration and over the… read more here.
Keywords: reorganization; actin myosin; simulated actin; motor ... See more keywords
Temperature-Dependent Activity of Motor Proteins: Energetics and Their Implications for Collective Behavior
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.610899
Abstract: Molecular motor proteins are an extremely important component of the cellular transport system that harness chemical energy derived from ATP hydrolysis to carry out directed mechanical motion inside the cells. Transport properties of these motors… read more here.
Keywords: activity motor; temperature dependent; motor proteins; implications collective ... See more keywords
Flagellar brake protein YcgR interacts with motor proteins MotA and FliG to regulate the flagellar rotation speed and direction
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1159974
Abstract: In E. coli and related species, flagellar brake protein YcgR responds to the elevated intracellular c-di-GMP, decreases the flagellar rotation speed, causes a CCW rotation bias, and regulates bacterial swimming. Boehm et al. suggested that… read more here.
Keywords: rotation speed; motor proteins; flagellar rotation; rotation ... See more keywords