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Published in 2020 at "Movement Disorders"
DOI: 10.1002/mds.28012
Abstract: The severity of motor symptoms in Parkinson's disease (PD) does not always correlate with the degree of nigral dopaminergic neuronal loss. Individuals with greater motor reserve may have milder motor signs than their striatal dopamine…
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Keywords:
reserve early;
brain network;
functional brain;
motor ... See more keywords
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Published in 2019 at "Journal of Parkinson's disease"
DOI: 10.3233/jpd-191762
Abstract: BACKGROUND Physical activity is associated with reduced risk of Parkinson's disease (PD). The explanations for this association are not completely elucidated. We use long-term PD-incidence data from long-distance skiers to study the relationship between exercise…
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Keywords:
physically active;
parkinson disease;
risk;
long distance ... See more keywords
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Published in 2021 at "Journal of Parkinson's disease"
DOI: 10.3233/jpd-212758
Abstract: BACKGROUND The concept of motor reserve explains the individual differences in motor deficits despite similar degrees of nigrostriatal dopamine depletion in Parkinson's disease (PD). OBJECTIVE To investigate glucocerebrosidase (GBA) variants as potential determinants of motor…
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Keywords:
updrs iii;
parkinson disease;
disease;
motor reserve ... See more keywords
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2
Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092166
Abstract: The ability to resiliently cope with neuropathological lesions is a key scientific concern. Accordingly, this study aims to investigate whether motor reserve (MR), likely to be boosted by exercise engagement in a lifetime, affects motor…
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Keywords:
brain networks;
motor;
motor reserve;
sca2 patients ... See more keywords