Opposing motors provide mechanical and functional robustness in the human spindle.
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DOI: 10.1016/j.devcel.2021.09.011
Abstract: At each cell division, the spindle self-organizes from microtubules and motors. In human spindles, the motors dynein and Eg5 generate contractile and extensile stress, respectively. Inhibiting dynein or its targeting factor NuMA leads to unfocused,… read more here.
Keywords: motors provide; functional robustness; opposing motors; provide mechanical ... See more keywords