Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15993
Abstract: Alveolar macrophages (AMs) contribute to airway inflammation and remodelling in allergic asthma. Calcaratarin D (CalD), a labdane diterpenoid from rhizomes of the medicinal plant Alpinia calcarata, has recently been shown to possess anti‐inflammatory properties. The… read more here.
Keywords: asthma via; mouse asthma; calcaratarin labdane; diterpenoid attenuates ... See more keywords
The Use of Mouse Asthma Models to Successfully Discover and Develop Novel Drugs
Sign Up to like & getrecommendations! Published in 2017 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000473699
Abstract: The past 20 years have seen a proliferation of scientific data on the pathophysiology of asthma. Most of these data were generated in mice using tool reagents, gene-deficient or transgenic animals. In contrast, studies on… read more here.
Keywords: use mouse; mouse models; mouse asthma; drug ... See more keywords