Characterization of Impaired Cerebrovascular Structure in APP/PS1 Mouse Brains
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.05.002
Abstract: Alzheimer's disease (AD) is defined by senile plaques, tauopathy and neuronal cell death in specific area of the brain. Recent studies suggest that neurovascular dysfunction may be an integral part of AD pathogenesis, contributing to… read more here.
Keywords: ps1 mouse; pathology; mouse brains; app ps1 ... See more keywords
Loss of Immunohistochemical Reactivity in Association With Handling-Induced Dark Neurons in Mouse Brains
Sign Up to like & getrecommendations! Published in 2020 at "Toxicologic Pathology"
DOI: 10.1177/0192623319896263
Abstract: The handling-induced dark neuron is a histological artifact observed in brain samples handled before fixation with aldehydes. To explore associations between dark neurons and immunohistochemical alterations in mouse brains, we examined protein products encoded by… read more here.
Keywords: dark neurons; handling induced; induced dark; mouse brains ... See more keywords
Simultaneous Observation of Mouse Cortical and Hippocampal Neural Dynamics under Anesthesia through a Cranial Microprism Window
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12080567
Abstract: The fluorescence microscope has been widely used to explore dynamic processes in vivo in mouse brains, with advantages of a large field-of-view and high spatiotemporal resolution. However, owing to background light and tissue scattering, the… read more here.
Keywords: simultaneous observation; brain; mouse brains; deep brain ... See more keywords
Loss of Corticostriatal Mu-Opioid Receptors in α-Synuclein Transgenic Mouse Brains
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12010063
Abstract: Ultrastructural, neurochemical, and molecular alterations within the striatum are associated with the onset and progression of Parkinson’s disease (PD). In PD, the dopamine-containing neurons in the substantia nigra pars compacta (SNc) degenerate and reduce dopamine-containing… read more here.
Keywords: loss corticostriatal; transgenic mouse; opioid receptors; loss ... See more keywords
Transcriptomic Analysis of mRNA Expression Profiles in the Microglia of Mouse Brains Infected with Rabies Viruses of Varying Virulence
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15061223
Abstract: Rabies is a lethal encephalitis caused by the rabies virus (RABV) with a fatality rate near 100% after the onset of clinical symptoms in humans and animals. Microglia are resident immune cells in the central… read more here.
Keywords: profiles microglia; expression profiles; mouse brains; mrna expression ... See more keywords