Mouse Genome Informatics (MGI): latest news from MGD and GXD
Sign Up to like & getrecommendations! Published in 2021 at "Mammalian Genome"
DOI: 10.1007/s00335-021-09921-0
Abstract: The Mouse Genome Informatics (MGI) database system combines multiple expertly curated community data resources into a shared knowledge management ecosystem united by common metadata annotation standards. MGI’s mission is to facilitate the use of the… read more here.
Keywords: mouse; informatics mgi; mouse genome; genome informatics ... See more keywords
i4mC-Mouse: Improved identification of DNA N4-methylcytosine sites in the mouse genome using multiple encoding schemes
Sign Up to like & getrecommendations! Published in 2020 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2020.04.001
Abstract: Graphical abstract In this work, we developed a new computational predictor called i4mC-Mouse for identifying 4mC sites in the mouse genome. A computational framework of i4mC-Mouse. read more here.
Keywords: identification dna; sites mouse; mouse genome; mouse improved ... See more keywords
Scaling up disease model discovery
Sign Up to like & getrecommendations! Published in 2017 at "Lab Animal"
DOI: 10.1038/laban.1342
Abstract: data and ranks their mutant lines as models for human diseases. “The goal is to use phenotype mapping along with whole genome variant prioritization and filtering to land on the most likely causative variant along… read more here.
Keywords: disease model; mouse genome; disease; impc ... See more keywords
The Black 6 gets company: De novo genomes assembled for 16 more mice
Sign Up to like & getrecommendations! Published in 2018 at "Lab Animal"
DOI: 10.1038/s41684-018-0197-2
Abstract: Not long after the initial publication of the human genome sequence, the Mouse Genome Sequencing Consortium followed suite with the first draft of a similar resource for the lab mouse (Nature 420, 520–562; 2002). The… read more here.
Keywords: mouse genome; genetics; reference; mice ... See more keywords
Transposable Element Interactions Shape the Ecology of the Deer Mouse Genome
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msad069
Abstract: Abstract The genomic landscape of transposable elements (TEs) varies dramatically across species, with some TEs demonstrating greater success in colonizing particular lineages than others. In mammals, long interspersed nuclear element (LINE) retrotransposons are typically more… read more here.
Keywords: ecology; deer mouse; mouse genome;
Understanding the Factors That Shape Patterns of Nucleotide Diversity in the House Mouse Genome
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msy188
Abstract: Abstract A major goal of population genetics has been to determine the extent by which selection at linked sites influences patterns of neutral nucleotide diversity in the genome. Multiple lines of evidence suggest that diversity… read more here.
Keywords: diversity; nucleotide diversity; mouse genome; patterns nucleotide ... See more keywords
4mCPred-CNN—Prediction of DNA N4-Methylcytosine in the Mouse Genome Using a Convolutional Neural Network
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.3390/genes12020296
Abstract: Among DNA modifications, N4-methylcytosine (4mC) is one of the most significant ones, and it is linked to the development of cell proliferation and gene expression. To know different its biological functions, the accurate detection of… read more here.
Keywords: 4mc sites; mouse genome; convolutional neural; 4mcpred cnn ... See more keywords
Functional Characterization of a Phf8 Processed Pseudogene in the Mouse Genome
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes14010172
Abstract: The majority of pseudogenes are generated when an RNA transcript is reverse-transcribed and integrated into the genome at a new location. Pseudogenes are often considered as an imperfect and silent copy of a functional gene… read more here.
Keywords: pseudogene; phf8; mouse genome; pseudogene mouse ... See more keywords