Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Nature biotechnology"
DOI: 10.1038/s41587-020-0549-5
Abstract: The gut microbiome is a malleable microbial community that can remodel in response to various factors, including diet, and contribute to the development of several chronic diseases, including atherosclerosis. We devised an in vitro screening… read more here.
Keywords: directed remodeling; mouse gut; gut microbiome; development ... See more keywords
Editing of a Specific Strain of Escherichia coli in the Mouse Gut Using Native Phages
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01804-22
Abstract: This report describes a gut engineering technique for investigation of the functions of a specific bacterium. Native phages with host specificity can knock down the corresponding E. coli strain in the mouse gut with limited… read more here.
Keywords: gut; bacterium; abundance; mouse gut ... See more keywords
The Type IV Pilus of Plasmid TP114 Displays Adhesins Conferring Conjugation Specificity and Is Important for DNA Transfer in the Mouse Gut Microbiota
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02303-21
Abstract: Conjugative plasmids are involved in horizontal gene transfer in the gut microbiota, which constitutes an important antibiotic resistance gene reservoir. However, the molecular mechanisms used by conjugative plasmids to select recipient bacteria and transfer at… read more here.
Keywords: dna; transfer; microbiota; gut microbiota ... See more keywords
Comparative evaluation of sequencing technologies and primer sets for mouse gut microbiota profiling
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2025.1584359
Abstract: Background Advancements in sequencing technologies, such as Illumina and Oxford Nanopore Technologies (ONT), have significantly improved microbiome research. However, variations in sequencing platforms, primer selection, and DNA quality may influence microbial diversity assessments, particularly in… read more here.
Keywords: sequencing technologies; gut microbiota; mouse gut; 16s rrna ... See more keywords