Ilepcimide inhibited sodium channel activity in mouse hippocampal neurons
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2020.106533
Abstract: Ilepcimide (ICM), a clinically effective antiepileptic drug, has been used in China for decades; however, its antiepileptic mechanism remains unclear. ICM is structurally similar to antiepileptic drug lamotrigine (LTG). LTG exerts its anticonvulsant effect by… read more here.
Keywords: channel activity; sodium channel; icm; mouse hippocampal ... See more keywords
The antiepileptic drug levetiracetam promotes neuroblast differentiation and expression of superoxide dismutase in the mouse hippocampal dentate gyrus via PI3K/Akt signalling
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.10.010
Abstract: Levetiracetam (LEV), a second-generation antiepileptic drug, is commonly prescribed to treat certain types of seizures. Few studies have investigated the effects of LEV on hippocampal neurogenesis and its related mechanisms. In the present study, we… read more here.
Keywords: pi3k; neuroblast differentiation; differentiation; mouse hippocampal ... See more keywords
Effect of (m)VD-hemopressin against Aβ1-42-induced oxidative stress and apoptosis in mouse hippocampal neurons
Sign Up to like & getrecommendations! Published in 2020 at "Peptides"
DOI: 10.1016/j.peptides.2019.170185
Abstract: Alzheimer's disease (AD) is a serious neurodegenerative disease. Senile plaques (SPs) composed of amyloid-β (Aβ) are typical features of AD. Aβ plays a key role in the disease and has the ability to induce other… read more here.
Keywords: stress injury; hippocampal neurons; apoptosis; stress ... See more keywords
Low-intensity ultrasound suppresses low-Mg2+-induced epileptiform discharges in juvenile mouse hippocampal slices.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neural engineering"
DOI: 10.1088/1741-2552/ab0b9a
Abstract: OBJECTIVE It has been shown that low-intensity ultrasound (LIUS) can suppress seizures in some laboratory studies. However, the mechanism of the suppression effect of LIUS remains unclear. The goal of this study is to investigate… read more here.
Keywords: hippocampal slices; intensity ultrasound; epileptiform discharges; mouse hippocampal ... See more keywords
Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Radiation Research"
DOI: 10.1093/jrr/rrx045
Abstract: Abstract Alzheimer’s disease (AD) is a neurodegenerative disease leading to progressive loss of memory and other cognitive functions. One of the well-known pathological markers of AD is the accumulation of amyloid-beta protein (Aβ), and its… read more here.
Keywords: radiofrequency electromagnetic; hippocampal neuronal; electromagnetic fields; mhz ... See more keywords
A Molecular Landscape of Mouse Hippocampal Neuromodulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2022.836930
Abstract: Adaptive neuronal circuit function requires a continual adjustment of synaptic network parameters known as “neuromodulation.” This process is now understood to be based primarily on the binding of myriad secreted “modulatory” ligands such as dopamine,… read more here.
Keywords: network; hippocampal neuromodulation; mouse hippocampal; molecular landscape ... See more keywords
Induction of Axonal Outgrowth in Mouse Hippocampal Neurons via Bacterial Magnetosomes
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084126
Abstract: Magnetosomes are membrane-enclosed iron oxide crystals biosynthesized by magnetotactic bacteria. As the biomineralization of bacterial magnetosomes can be genetically controlled, they have become promising nanomaterials for bionanotechnological applications. In the present paper, we explore a… read more here.
Keywords: bacterial magnetosomes; hippocampal neurons; outgrowth; mouse hippocampal ... See more keywords
Beta-Amyloid (Aβ1-42) Increases the Expression of NKCC1 in the Mouse Hippocampus
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27082440
Abstract: Alzheimer’s disease (AD) is a neurodegenerative disorder with an increasing need for developing disease-modifying treatments as current therapies only provide marginal symptomatic relief. Recent evidence suggests the γ-aminobutyric acid (GABA) neurotransmitter system undergoes remodeling in… read more here.
Keywords: nkcc1 expression; mouse hippocampal; expression levels; expression ... See more keywords