Guidelines for mouse and human DC generation.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of immunology"
DOI: 10.1002/eji.202249816
Abstract: This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and functional characterization of mouse and… read more here.
Keywords: article; human generation; generation; mouse human ... See more keywords
Guidelines for mouse and human DC functional assays.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of immunology"
DOI: 10.1002/eji.202249925
Abstract: This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and functional characterization of mouse and… read more here.
Keywords: human functional; cdc; guidelines mouse; functional assays ... See more keywords
In Vitro Direct Reprogramming of Mouse and Human Astrocytes to Induced Neurons.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0655-1_4
Abstract: Direct neuronal reprogramming, rewiring the epigenetic and transcriptional network of a differentiated cell type to neuron, apart from being a very promising approach for the treatment of brain injury and neurodegeneration, also offers a prime… read more here.
Keywords: neurons vitro; induced neurons; mouse human; human astrocytes ... See more keywords
Species-independent stimulation of osteogenic differentiation induced by osteoclasts.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2022.03.115
Abstract: The coupling of bone resorption and bone formation is well-recognized in the bone remodeling process, in which osteoblasts and osteoclasts are key players. However, the anabolic effect of human primary osteoclasts has rarely been reported… read more here.
Keywords: human osteoclasts; bone; differentiation; osteogenic differentiation ... See more keywords
Non-Canonical and Sexually Dimorphic X Dosage Compensation States in the Mouse and Human Germline
Sign Up to like & getrecommendations! Published in 2017 at "Developmental Cell"
DOI: 10.1016/j.devcel.2016.12.023
Abstract: Summary Somatic X dosage compensation requires two mechanisms: X inactivation balances X gene output between males (XY) and females (XX), while X upregulation, hypothesized by Ohno and documented in vivo, balances X gene with autosomal… read more here.
Keywords: dosage compensation; mouse human; non canonical; dosage ... See more keywords
CRIPSR/Cas9 Technology: Hypoimmunogenic Pluripotent Stem Cells Evade Immune Rejection in Fully Immunocompetent Allogeneic Recipients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2021.01.1806
Abstract: Purpose Induced pluripotent stem cells (iPSCs) are promising candidates for regenerative medicine. To overcome the allogeneic immune barrier, we created hypo-immune iPSCs using CRISPR/Cas9 editing strategies and demonstrate long-term survival of allografts without the need… read more here.
Keywords: pluripotent stem; ipscs; cas9 technology; stem cells ... See more keywords
CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light‐Zone Location and Predominant Low Antigen Affinity
Sign Up to like & getrecommendations! Published in 2017 at "Immunity"
DOI: 10.1016/j.immuni.2017.11.022
Abstract: Summary Memory B cells (MBCs) and plasma cells (PCs) constitute the two cellular outputs of germinal center (GC) responses that together facilitate long‐term humoral immunity. Although expression of the transcription factor BLIMP‐1 identifies cells undergoing… read more here.
Keywords: cell precursors; affinity; mouse human; precursors mouse ... See more keywords
Microglial transcription profiles in mouse and human are driven by APOE4 and sex
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.103238
Abstract: Summary Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). APOE4 is known to affect the function of microglia, but to what extent this gene drives microglial gene expression has… read more here.
Keywords: transcription profiles; profiles mouse; mouse human; sex ... See more keywords
Utilization of a mouse/human chimeric model for long term metabolic testing of human skin.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2019.106663
Abstract: Until now, ex vivo human skin explant utilization in tissue culture has consisted of limited short-term studies (less than a week). This short timeframe does not allow for the investigation of metabolic responses of complex… read more here.
Keywords: term; human skin; skin; mouse human ... See more keywords
Analysis and Comparison of Mouse and Human Brain Gangliosides via Two-Stage Matching of MS/MS Spectra
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c07070
Abstract: Glycosphingolipids (GSLs), including gangliosides, are essential components of the cell membrane. Because of their vital biological functions, a facile method for the analysis and comparison of GSLs in biological issues is desired. To this end,… read more here.
Keywords: two stage; mouse human; analysis; brain gangliosides ... See more keywords
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18512-7
Abstract: Understanding cell types and mechanisms of dental growth is essential for reconstruction and engineering of teeth. Therefore, we investigated cellular composition of growing and non-growing mouse and human teeth. As a result, we report an… read more here.
Keywords: mouse human; cell types; dental cell; cell ... See more keywords