BMP4 promotes mouse iPS cell differentiation to male germ cells via Smad1/5, Gata4, Id1 and Id2.
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DOI: 10.1530/rep-16-0292
Abstract: Generation of male germ cells from pluripotent cells could provide male gametes for treating male infertility and offer an ideal model for unveiling molecular mechanisms of spermatogenesis. However, the influence and exact molecular mechanisms, especially… read more here.
Keywords: mouse ips; ips cells; germ cells; germ cell ... See more keywords