Kcnn4 is a modifier gene of intestinal cystic fibrosis preventing lethality in the Cftr-F508del mouse
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DOI: 10.1038/s41598-018-27465-3
Abstract: Nearly 70% of cystic fibrosis (CF) patients bear the phenylalanine-508 deletion but disease severity differs greatly, and is not explained by the existence of different mutations in compound heterozygous. Studies demonstrated that genes other than CFTR… read more here.
Keywords: cystic fibrosis; modifier gene; mouse kcnn4; gene ... See more keywords