A 3D population-based brain atlas of the mouse lemur primate with examples of applications in aging studies and comparative anatomy
Sign Up to like & getrecommendations! Published in 2019 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2018.10.010
Abstract: &NA; The gray mouse lemur (Microcebus murinus) is a small prosimian of growing interest for studies of primate biology and evolution, and notably as a model organism of brain aging. As brain atlases are essential… read more here.
Keywords: mouse lemur; anatomy; atlas mouse; brain ... See more keywords
Comparative analyses of two primate species diverged by more than 60 million years show different rates but similar distribution of genome-wide UV repair events
Sign Up to like & getrecommendations! Published in 2021 at "BMC Genomics"
DOI: 10.1186/s12864-021-07898-3
Abstract: Background Nucleotide excision repair is the primary DNA repair mechanism that removes bulky DNA adducts such as UV-induced pyrimidine dimers. Correspondingly, genome-wide mapping of nucleotide excision repair with eXcision Repair sequencing (XR-seq), provides comprehensive profiling… read more here.
Keywords: wide repair; genome wide; mouse lemur; repair events ... See more keywords
Spontaneous Spongiform Brainstem Degeneration in a Young Mouse Lemur (Microcebus murinus) with Conspicuous Behavioral, Motor, Growth, and Ocular Pathologies.
Sign Up to like & getrecommendations! Published in 2018 at "Comparative medicine"
DOI: 10.30802/aalas-cm-18-000019
Abstract: Here we report a case of severe growth retardation and neurologic abnormalities in a female gray mouse lemur (Microcebus murinus), a small NHP species for which the genomic sequence recently became available. The female lemur… read more here.
Keywords: mouse lemur; lemur; lemur microcebus; motor ... See more keywords
Strengths and Weaknesses of the Gray Mouse Lemur (Microcebus murinus) as a Model for the Behavioral and Psychological Symptoms and Neuropsychiatric Symptoms of Dementia
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.01291
Abstract: To face the load of the prevalence of Alzheimer’s disease in the aging population, there is an urgent need to develop more translatable animal models with similarities to humans in both the symptomatology and physiopathology… read more here.
Keywords: mouse lemur; gray mouse; lemur microcebus; mouse ... See more keywords