Proteome‐transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2018.10.011
Abstract: ABSTRACT Epithelial cells and differentiated fiber cells represent distinct compartments in the ocular lens. While previous studies have revealed proteins that are preferentially expressed in epithelial vs. fiber cells, a comprehensive proteomics library comparing the… read more here.
Keywords: mouse lens; epithelium fibers; analysis; lens epithelium ... See more keywords
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.12.016
Abstract: Epithelial cell polarity, adhesion, proliferation, differentiation and survival are essential for morphogenesis of various organs and tissues including the ocular lens. The molecular mechanisms regulating the lens epithelial phenotype however, are not well understood. Here… read more here.
Keywords: mouse lens; ankg; morphogenesis; cell ... See more keywords
Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81611-y
Abstract: S100A4, a member of the S100 family of multifunctional calcium-binding proteins, participates in several physiological and pathological processes. In this study, we demonstrate that S100A4 expression is robustly induced in differentiating fiber cells of the… read more here.
Keywords: mouse lens; lens induces; s100a4; s100a4 mouse ... See more keywords