Gad1‐promotor‐driven GFP expression in non‐GABAergic neurons of the nucleus endopiriformis in a transgenic mouse line
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24673
Abstract: Transgenic animals have become a widely used model to identify and study specific cell types in whole organs. Promotor‐driven reporter gene labeling of the cells under investigation has promoted experimental efficacy to a large degree.… read more here.
Keywords: non gabaergic; mouse line; transgenic mouse; promotor driven ... See more keywords
Characterization of a novel Hoxa5eGFP mouse line
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.563
Abstract: Hox genes encode transcription factors that are important for establishing the body plan. Hoxa5 is a member of the mammalian Hox5 paralogous group that regulates the patterning and morphology of the cervical‐thoracic region of the… read more here.
Keywords: characterization novel; novel hoxa5egfp; hoxa5egfp mouse; mouse line ... See more keywords
Generation of a new mouse line with conditionally activated signaling through the BMP receptor, ACVR1: A tool to characterize pleiotropic roles of BMP functions
Sign Up to like & getrecommendations! Published in 2021 at "genesis"
DOI: 10.1002/dvg.23419
Abstract: BMP signaling plays pleiotropic roles in various tissues during embryogenesis and after birth. We have previously generated a constitutively activated Acvr1(ca‐Acvr1) transgenic mouse line (line L35) through pronuclei injection to investigate impacts of enhanced BMP… read more here.
Keywords: mouse line; line l35; line a11; line ... See more keywords
Generation of an Ihh‐mKate2‐Dre knock‐in mouse line
Sign Up to like & getrecommendations! Published in 2022 at "genesis"
DOI: 10.1002/dvg.23488
Abstract: Indian hedgehog (Ihh), a member of the Hh family, plays important roles in vertebrate development and homeostasis. To improve our understanding of the function of Ihh‐expressing cells and their progeny as well, we generate an… read more here.
Keywords: dre; dre knock; ihh; mouse line ... See more keywords
High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2017.01.003
Abstract: Objective α-cells are the second most prominent cell type in pancreatic islets and are responsible for producing glucagon to increase plasma glucose levels in times of fasting. α-cell dysfunction and inappropriate glucagon secretion occur in… read more here.
Keywords: glucagon creer; glucagon; mouse line; gene ... See more keywords
Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10956-w
Abstract: A GGGGCC hexanucleotide repeat expansion in intron 1 of chromosome 9 open reading frame 72 (C9ORF72) gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Repeat-associated non-ATG translation of… read more here.
Keywords: mouse line; repeat; motor; gfp pr28 ... See more keywords
Characterisation of lamina I anterolateral system neurons that express Cre in a Phox2a-Cre mouse line
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-97105-w
Abstract: A recently developed Phox2a::Cre mouse line has been shown to capture anterolateral system (ALS) projection neurons. Here, we used this line to test whether Phox2a-positive cells represent a distinct subpopulation among lamina I ALS neurons.… read more here.
Keywords: phox2a cre; line; phox2a; mouse line ... See more keywords
Selection for female traits of high fertility affects male reproductive performance and alters the testicular transcriptional profile
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-4288-z
Abstract: BackgroundMany genes important for reproductive performance are shared by both sexes. However, fecundity indices are primarily based on female parameters such as litter size. We examined a fertility mouse line (FL2), which has a considerably… read more here.
Keywords: reproductive performance; mouse line; performance; female traits ... See more keywords
Characterization of a Knock-In Mouse Line Expressing a Fusion Protein of κ Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging via CLARITY
Sign Up to like & getrecommendations! Published in 2020 at "eNeuro"
DOI: 10.1523/eneuro.0028-20.2020
Abstract: Abstract Activation of κ opioid receptor (KOR) produces analgesia, antipruritic effect, sedation and dysphoria. To characterize neuroanatomy of KOR at high resolutions and circumvent issues of specificity of KOR antibodies, we generated a knock-in mouse… read more here.
Keywords: mouse line; opioid receptor; line expressing; brain ... See more keywords
Generation of a Gal4-dependent gene recombination and illuminating mouse
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Animals"
DOI: 10.1538/expanim.21-0202
Abstract: Cell labeling technologies, including the Cre/loxP system, are powerful tools in developmental biology. Although the conventional Cre/loxP system has been extensively used to label the expression of specific genes, it is less frequently used for… read more here.
Keywords: gal4 dependent; cre recombinase; mouse; mouse line ... See more keywords