Derepression of matrix metalloproteinase gene transcription and an emphysema‐like phenotype in transcription factor Zbtb7c knockout mouse lungs
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13501
Abstract: Dysregulated matrix metalloproteinase (MMP) gene expression is a major cause of the degradation of lung tissue that is integral to emphysema pathogenesis. Cigarette smoking (CS) increases MMP gene expression, a major contributor to emphysema development.… read more here.
Keywords: mouse lungs; transcription; zbtb7c; matrix metalloproteinase ... See more keywords
Impact of different tissue dissociation protocols on endothelial cell recovery from developing mouse lungs
Sign Up to like & getrecommendations! Published in 2024 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24843
Abstract: Flow cytometry and fluorescence‐activated cell sorting are widely used to study endothelial cells, for which the generation of viable single‐cell suspensions is an essential first step. Two enzymatic approaches, collagenase A and dispase, are widely… read more here.
Keywords: cell; recovery; endothelial cell; mouse lungs ... See more keywords
Grading Bleomycin‐Induced Pulmonary Fibrosis in ex vivo Mouse Lungs Using Ultrasound Image Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ultrasound in Medicine"
DOI: 10.1002/jum.15448
Abstract: The aim of this study was to assess bleomycin‐induced pulmonary fibrosis on ex vivo mouse lungs using ultrasound image grading and texture analysis. read more here.
Keywords: bleomycin induced; fibrosis vivo; mouse lungs; induced pulmonary ... See more keywords
Correlations between Extracellular Matrix Components in Mouse Lungs during Chronic BCG-Induced Granulomatosis
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4155-1
Abstract: Correlations between extracellular matrix components in mouse lungs were examined during various terms of BCG-induced granulomatosis (on postinfection days 3, 30, 60, 90, and 180). During the development of pathological process, the revealed dynamic interrelations… read more here.
Keywords: mouse lungs; correlations extracellular; matrix components; extracellular matrix ... See more keywords
Influenza Virus Infection Induces ZBP1 Expression and Necroptosis in Mouse Lungs
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00286
Abstract: Programmed cell death and especially necroptosis, a programmed and regulated form of necrosis, have been recently implicated in the progression and outcomes of influenza in mouse models. Moreover, Z-DNA/RNA binding protein 1 (ZBP1) has been… read more here.
Keywords: mouse lungs; infection; necroptosis; iav infection ... See more keywords
Spatial Resolution of Mycobacterium tuberculosis Bacteria and Their Surrounding Immune Environments Based on Selected Key Transcripts in Mouse Lungs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.876321
Abstract: Mycobacterium tuberculosis (Mtb) bacilli are the causative agent of tuberculosis (TB), a major killer of mankind. Although it is widely accepted that local interactions between Mtb and the immune system in the tuberculous granuloma determine… read more here.
Keywords: mycobacterium tuberculosis; mouse lungs; tuberculosis; bacteria clusters ... See more keywords
Elucidation of the Molecular Pathways Involved in the Protective Effects of AUY-922 in LPS-Induced Inflammation in Mouse Lungs
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceuticals"
DOI: 10.3390/ph14060522
Abstract: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) cause thousands of deaths every year and are associated with high mortality rates (~40%) due to the lack of efficient therapies. Understanding the molecular mechanisms… read more here.
Keywords: mouse lungs; lps induced; induced inflammation; auy 922 ... See more keywords