Strobilanthes crispus bioactive subfraction inhibits tumor progression and improves hematological and morphological parameters in mouse mammary carcinoma model.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113522
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Locally known as 'pecah batu', 'bayam karang', 'keci beling' or 'batu jin', the Malaysian medicinal herb, Strobilanthes crispus (S. crispus), is traditionally used by the local communities as alternative or adjuvant remedy for… read more here.
Keywords: carcinoma model; mammary carcinoma; mouse mammary; tumor ... See more keywords
A dioxin‐like compound induces hyperplasia and branching morphogenesis in mouse mammary gland, through alterations in TGF‐&bgr;1 and aryl hydrocarbon receptor signaling
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.09.012
Abstract: &NA; Hexachlorobenzene (HCB) is a widespread environmental pollutant and a dioxin‐like compound that binds weakly to the aryl hydrocarbon receptor (AhR). Because AhR and transforming growth factor &bgr;1 (TGF‐&bgr;1) converge to regulate common signaling pathways,… read more here.
Keywords: hcb; mammary gland; mouse mammary; receptor ... See more keywords
Phosphotungstic acid-enhanced microcomputed tomography for quantitative visualization of mouse mammary gland morphology.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medical imaging"
DOI: 10.1117/1.jmi.10.s2.s22402
Abstract: Purpose Even though current techniques provide two-dimensional (2D) imaging of the mouse mammary gland, they fail to achieve high-resolution three-dimensional (3D) reconstruction and quantification. The objective of this study is to establish and evaluate quantitative… read more here.
Keywords: gland morphology; mouse mammary; mammary gland;
GosB Inhibits Triacylglycerol Synthesis and Promotes Cell Survival in Mouse Mammary Epithelial Cells
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/7394869
Abstract: It has been demonstrated that the activator protein related transcription factor Finkel-Biskis-Jinkins murine osteosarcoma B (GosB) is involved in preadipocyte differentiation and triacylglycerol synthesis. However, the role of GosB in regulating the synthesis of milk… read more here.
Keywords: epithelial cells; fatty acid; gosb; mouse mammary ... See more keywords
Abstract A05: Deep immunofluorescence imaging of solvent-cleared mouse mammary glands
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.advbc17-a05
Abstract: We seek to trace the progression of epithelial lesions originating from Lgr5+ cells in mouse mammary glands using the 3DISCO protocol for solvent-cleared tissue. Lineage tracing is increasingly being used to probe different cell types… read more here.
Keywords: lgr5 cells; mammary glands; solvent cleared; mouse mammary ... See more keywords
Single-Cell Transcriptomics Identifies Heterogeneity of Mouse Mammary Gland Fibroblasts With Distinct Functions, Estrogen Responses, Differentiation Processes, and Crosstalks With Epithelium
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.850568
Abstract: Fibroblasts have been shown to be one of the essential players for mammary gland organization. Here, we identify two major types of mouse mammary gland fibroblasts through single-cell RNA sequencing analysis: Dpp4 + fibroblasts and… read more here.
Keywords: mammary gland; mouse mammary; gland; single cell ... See more keywords
Modulation of Fibroblast Activity via Vitamin D3 Is Dependent on Tumor Type—Studies on Mouse Mammary Gland Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14194585
Abstract: Simple Summary This study, which was conducted in healthy mice and mice bearing three mouse mammary gland cancers—4T1, 67NR, and E0771—showed that the divergent effects of vitamin D3 supplementation (5000 IU) or deficiency (100 IU… read more here.
Keywords: mouse mammary; healthy mice; vitamin; factor ... See more keywords
Biochemical and Functional Characterization of Mouse Mammary Tumor Virus Full-Length Pr77Gag Expressed in Prokaryotic and Eukaryotic Cells
Sign Up to like & getrecommendations! Published in 2018 at "Viruses"
DOI: 10.3390/v10060334
Abstract: The mouse mammary tumor virus (MMTV) Pr77Gag polypeptide is an essential retroviral structural protein without which infectious viral particles cannot be formed. This process requires specific recognition and packaging of dimerized genomic RNA (gRNA) by… read more here.
Keywords: full length; pr77gag; mouse mammary; eukaryotic cells ... See more keywords
Mouse Mammary Tumor Virus (MMTV) and MMTV-like Viruses: An In-depth Look at a Controversial Issue
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14050977
Abstract: Since its discovery as a milk factor, mouse mammary tumor virus (MMTV) has been shown to cause mammary carcinoma and lymphoma in mice. MMTV infection depends upon a viral superantigen (sag)-induced immune response and exploits… read more here.
Keywords: mammary tumor; mouse mammary; mmtv like; tumor virus ... See more keywords
Global Down-regulation of Gene Expression Induced by Mouse Mammary Tumor Virus (MMTV) in Normal Mammary Epithelial Cells
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15051110
Abstract: Mouse mammary tumor virus (MMTV) is a betaretrovirus that causes breast cancer in mice. The mouse mammary epithelial cells are the most permissive cells for MMTV, expressing the highest levels of virus upon infection and… read more here.
Keywords: mouse mammary; mmtv expression; expression; epithelial cells ... See more keywords
Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy
Sign Up to like & getrecommendations! Published in 2019 at "Theranostics"
DOI: 10.7150/thno.31461
Abstract: Carbon monoxide and nitric oxide are two of the most important vasoprotective mediators. Their downregulation observed during vascular dysfunction, which is associated with cancer progression, leads to uncontrolled platelet activation. Therefore, the aim of our… read more here.
Keywords: corm deta; mammary gland; mouse mammary; cancer ... See more keywords