Modulation of NF-kB signaling by mercury compounds in mouse microglia cells and its relationship with glutathione levels
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.275
Abstract: Mercury (Hg) is widely known by its neurotoxicity albeit immunotoxicity occurs at lower exposure levels. Since microglia cells are the major representatives of the immune system in the CNS, we hypothesize Hg compounds disrupt microglia… read more here.
Keywords: mouse microglia; p50 p65; microglia cells; modulation signaling ... See more keywords
Atractylenolide-III suppresses lipopolysaccharide-induced inflammation via downregulation of toll-like receptor 4 in mouse microglia
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e08269
Abstract: Atractylenolide-III (AIII), a sesquiterpene compound isolated from the rhizome of Atractylodes macrocephala, has been reported to have anti-inflammatory effects in the peripheral organs. However, its effects on brain inflammation remain elusive. The present study investigated… read more here.
Keywords: toll like; mouse microglia; inflammation; like receptor ... See more keywords
Differential effects of TSPO ligands on mitochondrial function in mouse microglia cells
Sign Up to like & getrecommendations! Published in 2019 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2019.03.029
Abstract: The translocator protein 18 kDa (TSPO), initially characterized as peripheral benzodiazepine receptor, is a conserved outer mitochondrial membrane protein, implicated in cholesterol transport thereby affecting steroid hormone biosynthesis, as well as in general mitochondrial function related… read more here.
Keywords: mouse microglia; function; mitochondrial function; effects tspo ... See more keywords
Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108508
Abstract: Microglia, the resident immune cells of the central nervous system, play important roles in brain homeostasis as well as in neuroinflammation, neurodegeneration, neurovascular diseases, and traumatic brain injury. In this context, components of the endocannabinoid… read more here.
Keywords: anti inflammatory; mouse microglia; bv2 mouse; pro inflammatory ... See more keywords