The effects of graphene quantum dots on the maturation of mouse oocytes and development of offspring
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28062
Abstract: Recently, graphene nanomaterials have attracted tremendous attention and have been utilized in various fields because of their excellent mechanical, thermal, chemical, optical properties, and good biocompatibility, especially in biomedical aspects. However, there is a concern… read more here.
Keywords: graphene quantum; mouse oocytes; maturation mouse; effects graphene ... See more keywords
2,4‐DCP compromises the fertilization capacity of mouse oocytes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30403
Abstract: 2,4‐DCP (2,4‐dichlorophenol) is an environmental estrogen that is ubiquitously distributed in the environment and widely used to produce herbicides and pharmaceutical intermediates. Although 2,4‐DCP is suspected to have endocrine disruption, the reproductive toxicity of 2,4‐DCP… read more here.
Keywords: fertilization; mouse oocytes; compromises fertilization; dcp ... See more keywords
Toxic effects of AZD1208 on mouse oocytes and its possible mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30835
Abstract: AZD1208, a pan‐inhibitor that can effectively inhibit PIM kinase, is used for the treatment of advanced solid tumors and malignant lymphomas. Numerous studies have proved its curative effects while its potential cellular toxicity on reproduction… read more here.
Keywords: effects azd1208; toxic effects; mouse oocytes; treatment ... See more keywords
The CARD Method for Simple Vitrification of Mouse Oocytes: Advantages and Applications.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8831-0_13
Abstract: A light modification on the mouse embryos CARD simple vitrification protocol makes it possible the oocyte freezing. This rapid and handy method for cryopreservation of mouse oocytes has many advantages and multiple applications like banking… read more here.
Keywords: simple vitrification; mouse oocytes; mouse; card method ... See more keywords
Superovulation alters DNA methyltransferase protein expression in mouse oocytes and early embryos
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-017-1087-z
Abstract: PurposeDNA methylation is an epigenetic mechanism that plays critical roles during mammalian oocyte and preimplantation embryo development. It is achieved by adding a methyl group to the fifth carbon atom of cytosine residues within cytosine-phosphate-guanine… read more here.
Keywords: mouse oocytes; oocytes early; superovulation; expression ... See more keywords
Citrinin exposure disrupts organelle distribution and functions in mouse oocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental research"
DOI: 10.1016/j.envres.2020.109476
Abstract: Citrinin (CTN) is a secondary fungal metabolite produced by several species of Aspergillins and Penicillins, and it is widely found in vegetable-derived foods such as cereals and fermented rice-based food supplements. Previous studies indicated that… read more here.
Keywords: distribution functions; ctn exposure; mouse oocytes; exposure ... See more keywords
Dynamic organelle distribution initiates actin-based spindle migration in mouse oocytes
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-019-14068-3
Abstract: Migration of meiosis-I (MI) spindle from the cell center to a sub-cortical location is a critical step for mouse oocytes to undergo asymmetric meiotic cell division. In this study, we investigate the mechanism by which… read more here.
Keywords: spindle migration; mouse oocytes; migration; dynamic organelle ... See more keywords
Artificially decreasing cortical tension generates aneuploidy in mouse oocytes
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15470-y
Abstract: Human and mouse oocytes’ developmental potential can be predicted by their mechanical properties. Their development into blastocysts requires a specific stiffness window. In this study, we combine live-cell and computational imaging, laser ablation, and biophysical… read more here.
Keywords: cortical tension; mouse oocytes; artificially decreasing; decreasing cortical ... See more keywords
Mechanisms for the species difference between mouse and pig oocytes in their sensitivity to glucorticoids†
Sign Up to like & getrecommendations! Published in 2017 at "Biology of Reproduction"
DOI: 10.1093/biolre/iox026
Abstract: Abstract Although in vitro exposure to physiological concentrations of glucorticoids did not affect maturation of mouse oocytes, it significantly inhibited nuclear maturation of pig oocytes. Studies on this species difference in oocyte sensitivity to glucocorticoids… read more here.
Keywords: pig; maturation; mouse oocytes; species difference ... See more keywords
Glucocorticoid receptor isoforms and effects of glucocorticoids in ovulated mouse oocytes and preimplantation embryos†
Sign Up to like & getrecommendations! Published in 2018 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioy196
Abstract: ABSTRACT To investigate possible involvement of glucocorticoid receptor (GR) in mediating effects of maternal stress or therapeutically administered glucocorticoids on early embryo, we analyzed the expression of GR subtypes in ovulated mouse oocytes and preimplantation… read more here.
Keywords: ovulated mouse; preimplantation embryos; mouse oocytes; glucocorticoid ... See more keywords
O-169 Conventional ovarian stimulation with gonadotropins depletes the developmental proteome of mouse oocytes, reducing their size and compromising their fetal yield
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab127.050
Abstract: Does conventional ovarian stimulation with gonadotropins alter the molecular composition, size, and developmental fitness of superovulated mouse oocytes? Ovarian stimulation perturbs 31% of developmental proteome vs. 2% of transcriptome, yielding smaller oocytes that form blastocysts… read more here.
Keywords: stimulation; mouse oocytes; superovulation; ovarian stimulation ... See more keywords