The effects of graphene quantum dots on the maturation of mouse oocytes and development of offspring
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28062
Abstract: Recently, graphene nanomaterials have attracted tremendous attention and have been utilized in various fields because of their excellent mechanical, thermal, chemical, optical properties, and good biocompatibility, especially in biomedical aspects. However, there is a concern… read more here.
Keywords: graphene quantum; mouse oocytes; maturation mouse; effects graphene ... See more keywords
2,4‐DCP compromises the fertilization capacity of mouse oocytes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30403
Abstract: 2,4‐DCP (2,4‐dichlorophenol) is an environmental estrogen that is ubiquitously distributed in the environment and widely used to produce herbicides and pharmaceutical intermediates. Although 2,4‐DCP is suspected to have endocrine disruption, the reproductive toxicity of 2,4‐DCP… read more here.
Keywords: fertilization; mouse oocytes; compromises fertilization; dcp ... See more keywords
Toxic effects of AZD1208 on mouse oocytes and its possible mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30835
Abstract: AZD1208, a pan‐inhibitor that can effectively inhibit PIM kinase, is used for the treatment of advanced solid tumors and malignant lymphomas. Numerous studies have proved its curative effects while its potential cellular toxicity on reproduction… read more here.
Keywords: effects azd1208; toxic effects; mouse oocytes; treatment ... See more keywords
Phospholipase D2 Regulates Microtubule Acetylation by Modulating Gsk3β‐Tau Signaling in Mouse Oocytes During Meiotic Maturation
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.70051
Abstract: Phospholipase D2 (PLD2) modulates cytoskeletal dynamics and membrane trafficking processes by converting phosphatidylcholine (PC) into phosphatidic acid (PA) and choline within somatic cells. Nonetheless, the role in oocyte meiosis remains largely unknown. Here, we demonstrate… read more here.
Keywords: pld2; tau; gsk3 tau; mouse oocytes ... See more keywords
The CARD Method for Simple Vitrification of Mouse Oocytes: Advantages and Applications.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8831-0_13
Abstract: A light modification on the mouse embryos CARD simple vitrification protocol makes it possible the oocyte freezing. This rapid and handy method for cryopreservation of mouse oocytes has many advantages and multiple applications like banking… read more here.
Keywords: simple vitrification; mouse oocytes; mouse; card method ... See more keywords
Superovulation alters DNA methyltransferase protein expression in mouse oocytes and early embryos
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-017-1087-z
Abstract: PurposeDNA methylation is an epigenetic mechanism that plays critical roles during mammalian oocyte and preimplantation embryo development. It is achieved by adding a methyl group to the fifth carbon atom of cytosine residues within cytosine-phosphate-guanine… read more here.
Keywords: mouse oocytes; oocytes early; superovulation; expression ... See more keywords
Citrinin exposure disrupts organelle distribution and functions in mouse oocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental research"
DOI: 10.1016/j.envres.2020.109476
Abstract: Citrinin (CTN) is a secondary fungal metabolite produced by several species of Aspergillins and Penicillins, and it is widely found in vegetable-derived foods such as cereals and fermented rice-based food supplements. Previous studies indicated that… read more here.
Keywords: distribution functions; ctn exposure; mouse oocytes; exposure ... See more keywords
Dynamic organelle distribution initiates actin-based spindle migration in mouse oocytes
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-019-14068-3
Abstract: Migration of meiosis-I (MI) spindle from the cell center to a sub-cortical location is a critical step for mouse oocytes to undergo asymmetric meiotic cell division. In this study, we investigate the mechanism by which… read more here.
Keywords: spindle migration; mouse oocytes; migration; dynamic organelle ... See more keywords
Artificially decreasing cortical tension generates aneuploidy in mouse oocytes
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15470-y
Abstract: Human and mouse oocytes’ developmental potential can be predicted by their mechanical properties. Their development into blastocysts requires a specific stiffness window. In this study, we combine live-cell and computational imaging, laser ablation, and biophysical… read more here.
Keywords: cortical tension; mouse oocytes; artificially decreasing; decreasing cortical ... See more keywords
Taurine, alpha lipoic acid and vitamin B6 ameliorate the reduced developmental competence of immature mouse oocytes exposed to methylglyoxal
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-66785-5
Abstract: Advanced glycation end products (AGEs) are the final products of the Maillard reaction, formed through the interaction of carbohydrates and proteins. Reactive dicarbonyl compounds such as methylglyoxal (MGO) serve as precursors for AGEs formation. Elevated… read more here.
Keywords: developmental competence; glycation; competence; mouse oocytes ... See more keywords
Mechanisms for the species difference between mouse and pig oocytes in their sensitivity to glucorticoids†
Sign Up to like & getrecommendations! Published in 2017 at "Biology of Reproduction"
DOI: 10.1093/biolre/iox026
Abstract: Abstract Although in vitro exposure to physiological concentrations of glucorticoids did not affect maturation of mouse oocytes, it significantly inhibited nuclear maturation of pig oocytes. Studies on this species difference in oocyte sensitivity to glucocorticoids… read more here.
Keywords: pig; maturation; mouse oocytes; species difference ... See more keywords