Effects of S‐pindolol in mouse pancreatic and lung cancer cachexia models
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13249
Abstract: It is known that S‐pindolol attenuates muscle loss in animal models of cancer cachexia and sarcopenia. In cancer cachexia, it also significantly reduced mortality and improved cardiac function, which is strongly compromised in cachectic animals. read more here.
Keywords: mouse pancreatic; cancer cachexia; effects pindolol; pindolol mouse ... See more keywords
Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone Treatment.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00668
Abstract: We combine liquid chromatography coupled with ion mobility spectrometry-mass spectrometry to elucidate how short exposure to corticosterone (Cort) alters the output of mouse pancreatic islet hormones. The workflow enables the robust separation of mouse insulin… read more here.
Keywords: mouse pancreatic; islet; corticosterone; pancreatic peptide ... See more keywords
A mouse pancreatic organoid model to compare PD-L1 blocking antibodies
Sign Up to like & getrecommendations! Published in 2022 at "mAbs"
DOI: 10.1080/19420862.2022.2139886
Abstract: ABSTRACT Immune checkpoint inhibitors (ICIs) have changed the therapeutic landscape for cancer patients, but diabetes, a rare, severe immune-related endocrinopathy, is linked to ICI therapy. It is unclear whether glycosylation of ICIs may play a… read more here.
Keywords: blocking antibodies; pancreatic organoid; mouse pancreatic; organoid model ... See more keywords
Abstract LB-262: Design, synthesis, and efficacy of MYC inhibitors in mouse pancreatic cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-lb-262
Abstract: Therapeutic inhibition of the MYC oncoprotein action for cancer treatment is a challenging aim and various anti-MYC approaches, including the development of small-molecule candidate drugs, are being actively pursued. Using genetically-modified mouse models of cancer,… read more here.
Keywords: mouse pancreatic; pancreatic cancer; efficacy; cancer ... See more keywords
Adrenomedullin and its receptors are expressed in mouse pancreatic β-cells and suppresses insulin synthesis and secretion
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0265890
Abstract: Gestational diabetes mellitus (GDM) is associated with defective pancreatic β-cell adaptation in pregnancy, but the underlying mechanism remains obscure. Our previous studies demonstrated that GDM women display increased plasma adrenomedullin (ADM) levels, and non-obese GDM… read more here.
Keywords: mouse pancreatic; adrenomedullin; secretion; receptors expressed ... See more keywords
Identification of a novel lncRNA (G3R1) regulated by GLIS3 in pancreatic β-cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-20-0082
Abstract: Recent advances in high throughput RNA sequencing have revealed that, in addition to messenger RNAs (mRNAs), long non-coding RNAs (lncRNAs) play an important role in the regulation of many cell functions and of organ development.… read more here.
Keywords: mouse pancreatic; g3r1; glis3; identification novel ... See more keywords
Erratum. Genetic Disruption of Adenosine Kinase in Mouse Pancreatic β-Cells Protects Against High-Fat Diet–Induced Glucose Intolerance. Diabetes 2017;66:1928–1938
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes"
DOI: 10.2337/db17-er12f
Abstract: In the article listed above, Yassan Abdolazimi’s name was inadvertently misspelled in the … read more here.
Keywords: mouse pancreatic; adenosine kinase; genetic disruption; kinase mouse ... See more keywords
Effects of Low Intensity Continuous Ultrasound (LICU) on Mouse Pancreatic Tumor Explants
Sign Up to like & getrecommendations! Published in 2017 at "Applied Sciences"
DOI: 10.3390/app7121275
Abstract: This paper describes the effects of low intensity continuous ultrasound (LICU) on the inflammatory response of mouse pancreatic tumor explants. While there are many reports focusing on the application of low-intensity pulsed ultrasound (LIPUS) on… read more here.
Keywords: mouse pancreatic; pancreatic tumor; tumor explants; low intensity ... See more keywords