Citalopram prevents sleep-deprivation-induced reduction in CaMKII-CREB-BDNF signaling in mouse prefrontal cortex
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DOI: 10.1016/j.brainresbull.2019.11.007
Abstract: Curtailment of sleep in modern society leads to a spectrum of neuropsychiatric disorders. However, the molecular mechanisms underlying the effects of sleep deprivation (SD) remain elusive and currently there is no effective therapy to alleviate… read more here.
Keywords: prefrontal cortex; mouse prefrontal; sleep deprivation; bdnf ... See more keywords
Mouse prefrontal cortex represents learned rules for categorization
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DOI: 10.1038/s41586-021-03452-z
Abstract: The ability to categorize sensory stimuli is crucial for an animal’s survival in a complex environment. Memorizing categories instead of individual exemplars enables greater behavioural flexibility and is computationally advantageous. Neurons that show category selectivity… read more here.
Keywords: categorization; cortex; represents learned; mouse prefrontal ... See more keywords
Dynamics of social representation in the mouse prefrontal cortex
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DOI: 10.1038/s41593-019-0531-z
Abstract: The prefrontal cortex (PFC) plays an important role in regulating social functions in mammals, and its dysfunction has been linked to social deficits in neurodevelopmental disorders. Yet little is known of how the PFC encodes… read more here.
Keywords: social representation; mouse prefrontal; social representations; dynamics social ... See more keywords