Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10498-1
Abstract: Spatiotemporally synchronised neuronal activity is central to sensation, motion and cognition. Brain circuits consist of dynamically interconnected neuronal cell-types, thus elucidating how neuron types synergise within the network is key to understand the neuronal orchestra.… read more here.
Keywords: network; mouse primary; neuronal cell; primary visual ... See more keywords
Novel stimuli evoke excess activity in the mouse primary visual cortex
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2108882119
Abstract: Significance Rapid detection and processing of stimulus novelty are key elements of adaptive behavior. Predictive coding theories postulate that novel stimuli should be encoded differently from familiar stimuli. Here, we show that the majority of… read more here.
Keywords: primary visual; visual cortex; mouse primary; activity ... See more keywords
Zika virus-induced hyper excitation precedes death of mouse primary neuron
Sign Up to like & getrecommendations! Published in 2018 at "Virology Journal"
DOI: 10.1186/s12985-018-0989-4
Abstract: BackgroundZika virus infection in new born is linked to congenital syndromes, especially microcephaly. Studies have shown that these neuropathies are the result of significant death of neuronal progenitor cells in the central nervous system of… read more here.
Keywords: death; mouse primary; zika virus; virus infection ... See more keywords
Muscarinic Modulation of SK2-Type K+ Channels Promotes Intrinsic Plasticity in L2/3 Pyramidal Neurons of the Mouse Primary Somatosensory Cortex
Sign Up to like & getrecommendations! Published in 2020 at "eNeuro"
DOI: 10.1523/eneuro.0453-19.2020
Abstract: Abstract Muscarinic acetylcholine receptors (mAChRs) inhibit small-conductance calcium-activated K+ channels (SK channels) and enhance synaptic weight via this mechanism. SK channels are also involved in activity-dependent plasticity of membrane excitability (“intrinsic plasticity”). Here, we investigate… read more here.
Keywords: mouse primary; plasticity; sk2; intrinsic plasticity ... See more keywords
Mapping the Plasticity of Morphology, Molecular Properties and Function in Mouse Primary Microglia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.811061
Abstract: Microglia exert diverse functions by responding in diverse ways to different stimuli, yet little is known about the plasticity of various phenotypes that microglia display. We used interferon (IFN)-γ, interleukin (IL)-4 and IL-10 to induce… read more here.
Keywords: mouse primary; phenotype; plasticity; primary microglia ... See more keywords
GB1a Activates SIRT6 to Regulate Lipid Metabolism in Mouse Primary Hepatocytes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119540
Abstract: Lipid accumulation, oxidative stress, and inflammation in hepatocytes are features of nonalcoholic fatty liver disease (NAFLD). Garcinia biflavonoid 1a (GB1a) is a natural product capable of hepatic protection. In this study, the effect of GB1a… read more here.
Keywords: mouse primary; gb1a reduced; primary hepatocytes; gb1a ... See more keywords