Physiological assessment of high glucose neurotoxicity in mouse and rat retinal explants
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24805
Abstract: One of the tissues of the central nervous system most affected by diabetes is the retina. Despite a growing understanding of the biochemical processes involved in glucose toxicity, little is known about the physiological consequences… read more here.
Keywords: retinal explants; physiological assessment; high glucose; assessment high ... See more keywords
Genome Editing in Mouse and Rat by Electroporation.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7128-2_7
Abstract: Many knock-out/knock-in mouse and rat strains have been produced by genome editing techniques using engineered endonucleases, including zinc finger nuclease (ZFN), transcription activator-like effector nuclease (TALEN), or clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9. Microinjection… read more here.
Keywords: engineered endonucleases; electroporation; genome editing; mouse rat ... See more keywords
Quantification of cyclocreatine in mouse and rat plasma using hydrophilic‐interaction ultra‐performance liquid chromatography‐tandem mass spectrometry
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.07.049
Abstract: HighlightsRapid, selective, accurate and reproducible HILIC UPLC–MS/MS method to quantify cyclocreatine was developed.Method provided good retention of cyclocreatine with no interference from mouse and rat plasma.The pharmacokinetic parameters of cyclocreatine after oral administration are reported.… read more here.
Keywords: cyclocreatine; rat plasma; plasma; mouse rat ... See more keywords
Mouse↔rat aggregation chimaeras can develop to adulthood.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.05.002
Abstract: In order to examine interactions between cells originating from different species during embryonic development we constructed interspecific mouse↔rat chimaeras by aggregation of 8-cell embryos. Embryos of both species expressed different fluorescent markers (eGFP and DsRed),… read more here.
Keywords: aggregation; rat cells; adulthood; rat ... See more keywords
Signal regulatory protein alpha is a conserved marker for mouse and rat spermatogonial stem cells
Sign Up to like & getrecommendations! Published in 2023 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioad006
Abstract: Abstract Characterization of spermatogonial stem cells (SSCs) has been hampered by their low frequency and lack of features that distinguish them from committed spermatogonia. Few conserved SSC markers have been discovered. To identify a new… read more here.
Keywords: mouse rat; marker; spermatogonial stem; stem cells ... See more keywords
Photoacoustics resolves species-specific differences in hemoglobin concentration and oxygenation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.25.9.095002
Abstract: Abstract. Significance: Photoacoustic imaging (PAI) enables the detection of blood hemoglobin (HB) concentration and oxygenation (sO2) with high contrast and resolution. Despite the heavy use of photoacoustically determined total hemoglobin (THb) and oxygenation (sO2) biomarkers… read more here.
Keywords: blood; species specific; mouse rat; concentration oxygenation ... See more keywords
The mouse and the rat in surgical research. The anesthetic approach
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Hellenic Veterinary Medical Society"
DOI: 10.12681/jhvms.15633
Abstract: Ο μυς και ο eπίμυς προτιμούνται κυρίως ως ζώα eργαστηρίου σe σχέση μe τα άλλα ζωικά πρότυπα. Η πeιραματική χeιρουργική απαιτeί την αναισθησία και αναλγησία των ζώων, για την eξασφάλιση eπαρκούς ακινητοποίησής τους, μeίωσης του… read more here.
Keywords: anesthetic approach; rat surgical; surgical research; mouse rat ... See more keywords
Toxicological effects of micro/nano-plastics on mouse/rat models: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2023.1103289
Abstract: Micro/nano-plastics (MNPs) are considered a heterogeneous class of environmental contaminants that cause multiple toxic effects on biological species. As the commonly used mammalian models to study the effects of MNPs with regard to their toxic… read more here.
Keywords: mouse rat; effects mnps; rat models; systematic review ... See more keywords
Functional and Pharmacological Comparison of Human, Mouse, and Rat Organic Cation Transporter 1 toward Drug and Pesticide Interaction
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21186871
Abstract: Extrapolation from animal to human data is not always possible, because several essential factors, such as expression level, localization, as well as the substrate selectivity and affinity of relevant transport proteins, can differ between species.… read more here.
Keywords: human mouse; interaction; organic cation; rat ... See more keywords
MicroRNAs in mouse and rat models of experimental epilepsy and potential therapeutic targets
Sign Up to like & getrecommendations! Published in 2023 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.369093
Abstract: Epilepsy is a common and serious neurological disease that causes recurrent seizures. The brain damage caused by seizures can lead to depression, anxiety, cognitive impairment, or disability. In almost all cases chronic seizures are difficult… read more here.
Keywords: mouse rat; seizure; micrornas mouse; models experimental ... See more keywords