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Published in 2019 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24684
Abstract: Combinatorial expression of Brn3 transcription factors is required for the development of cell‐specific morphologies in retinal ganglion cells (RGCs). The molecular mechanisms by which Brn3s regulate RGC type specific features are largely unexplored. We previously…
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Keywords:
differential expression;
mouse retina;
expression subcellular;
subcellular localization ... See more keywords
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Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.06.063
Abstract: To understand computation in a neural circuit requires a complete synaptic connectivity map and a thorough grasp of the information-processing tasks performed by the circuit. Here, we dissect a microcircuit in the mouse retina in…
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Keywords:
aii amacrine;
mouse retina;
synaptic transfer;
rod ... See more keywords
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Published in 2017 at "Neuroscience Research"
DOI: 10.1016/j.neures.2016.09.012
Abstract: ATP activates P2X receptors and acts as a neurotransmitter in the nervous system. We have previously reported that P2X receptors modulate the firing rate of retinal ganglion cells. Since many subtypes of P2X receptors are…
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Keywords:
p2x receptors;
intravitreal injection;
p2x;
mouse retina ... See more keywords
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Published in 2022 at "Journal of anatomy"
DOI: 10.1111/joa.13651
Abstract: Chemical and electrical synapses (gap junctions) are widely prevalent in the nervous system. Gap junctions emerge long before chemical synapses, allowing communication between developing cells, and are thought to be involved in establishing neural circuits.…
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Keywords:
cx45 cx36;
plexiform layers;
retina;
gap junctions ... See more keywords
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Published in 2022 at "Journal of anatomy"
DOI: 10.1111/joa.13653
Abstract: The precise specification of cellular fate is thought to ensure the production of the correct number of neurons within a population. Programmed cell death may be an additional mechanism controlling cell number, believed to refine…
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Keywords:
rod bipolar;
cell;
mouse retina;
plasticity ... See more keywords
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Published in 2022 at "Microcirculation"
DOI: 10.1111/micc.12752
Abstract: The neonatal mouse retina is a well‐characterized experimental model for investigating factors impacting retinal angiogenesis and inner blood‐retinal barrier (BRB) integrity. Retinoic acid (RA) is an essential signaling molecule. RA is needed for vasculogenic development…
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Keywords:
neonatal mouse;
barrier;
retina;
mouse ... See more keywords
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Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abq7219
Abstract: Many neurodegenerative diseases cause degeneration of specific types of neurons. For example, glaucoma leads to death of retinal ganglion cells, leaving other neurons intact. Neurons are not regenerated in the adult mammalian central nervous system.…
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Keywords:
ller glia;
ganglion;
ganglion like;
adult mouse ... See more keywords
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Published in 2018 at "Journal of neurophysiology"
DOI: 10.1152/jn.00716.2017
Abstract: Direction selectivity is a fundamental computation in the visual system and is first computed by the direction-selective circuit in the mammalian retina. Although landmark discoveries on the neural basis of direction selectivity have been made…
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Keywords:
direction;
motion;
mouse retina;
motion detection ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0176905
Abstract: The mouse retina comprises seven major cell types that exist in differing proportions. They are generated from multipotent progenitors in a stochastic manner, such that the relative frequency of any given type generated changes over…
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Keywords:
blimp1 prdm1;
blimp1;
enhancer;
mouse retina ... See more keywords
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Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0262763
Abstract: The mouse has dichromatic color vision based on two different types of opsins: short (S)- and middle (M)-wavelength-sensitive opsins with peak sensitivity to ultraviolet (UV; 360 nm) and green light (508 nm), respectively. In the…
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Keywords:
vision;
image;
image statistics;
statistics mouse ... See more keywords
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Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0270-22.2022
Abstract: Abstract Behavioral interactions with moving objects are challenged by response latencies within the sensory and motor nervous systems. In vision, the combined latency from phototransduction and synaptic transmission from the retina to central visual areas…
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Keywords:
phase advancing;
retina;
advancing common;
common property ... See more keywords